The effect of high dose digoxin on cytokines in healthy dogs
Background: Tumor necrosis factor (TNF)-α and interleukin (IL)-1β are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs fo...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2002-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1080/096293502900000122 |
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Summary: | Background: Tumor necrosis factor (TNF)-α and interleukin (IL)-1β are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs for the treatment of heart failure. |
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ISSN: | 0962-9351 1466-1861 |