Immune Thrombocytopenia in a Child with Neuroblastoma
Thrombocytopenia is a frequent finding in patients with solid tumors. It is usually caused by bone marrow infiltration or by myelosuppression due to anticancer therapy; however immune thrombocytopenia (ITP) associated with solid tumors is rare. Neuroblastoma is the most common extracranial solid tum...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2017/1329489 |
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| _version_ | 1832552203248730112 |
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| author | Hasan Tarkan Ikizoglu Inci Ayan Fatma Tokat Tulay Tecimer Gonca Topuzlu Tekant |
| author_facet | Hasan Tarkan Ikizoglu Inci Ayan Fatma Tokat Tulay Tecimer Gonca Topuzlu Tekant |
| author_sort | Hasan Tarkan Ikizoglu |
| collection | DOAJ |
| description | Thrombocytopenia is a frequent finding in patients with solid tumors. It is usually caused by bone marrow infiltration or by myelosuppression due to anticancer therapy; however immune thrombocytopenia (ITP) associated with solid tumors is rare. Neuroblastoma is the most common extracranial solid tumor in children. Here we report the case of a two-year-nine-month-old patient with adrenal neuroblastoma who presented with ITP. Paraneoplastic ITP was considered in the differential diagnosis. Bone marrow infiltration and other causes of thrombocytopenia were excluded and the patient was treated with intravenous immunoglobulin and tumor resection. Platelet count increased rapidly after surgery and complete remission of ITP was achieved. |
| format | Article |
| id | doaj-art-0f6cdbda4da7457db91d74c728f6e67e |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-0f6cdbda4da7457db91d74c728f6e67e2025-02-03T05:59:16ZengWileyCase Reports in Pediatrics2090-68032090-68112017-01-01201710.1155/2017/13294891329489Immune Thrombocytopenia in a Child with NeuroblastomaHasan Tarkan Ikizoglu0Inci Ayan1Fatma Tokat2Tulay Tecimer3Gonca Topuzlu Tekant4Department of Pediatrics, Acibadem University Medical Faculty, Istanbul, TurkeyDepartment of Pediatrics, Acibadem Maslak Hospital, Istanbul, TurkeyDepartment of Pathology, Acibadem Maslak Hospital, Istanbul, TurkeyDepartment of Pathology, Acibadem Maslak Hospital, Istanbul, TurkeyDepartment of Pediatric Surgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, TurkeyThrombocytopenia is a frequent finding in patients with solid tumors. It is usually caused by bone marrow infiltration or by myelosuppression due to anticancer therapy; however immune thrombocytopenia (ITP) associated with solid tumors is rare. Neuroblastoma is the most common extracranial solid tumor in children. Here we report the case of a two-year-nine-month-old patient with adrenal neuroblastoma who presented with ITP. Paraneoplastic ITP was considered in the differential diagnosis. Bone marrow infiltration and other causes of thrombocytopenia were excluded and the patient was treated with intravenous immunoglobulin and tumor resection. Platelet count increased rapidly after surgery and complete remission of ITP was achieved.http://dx.doi.org/10.1155/2017/1329489 |
| spellingShingle | Hasan Tarkan Ikizoglu Inci Ayan Fatma Tokat Tulay Tecimer Gonca Topuzlu Tekant Immune Thrombocytopenia in a Child with Neuroblastoma Case Reports in Pediatrics |
| title | Immune Thrombocytopenia in a Child with Neuroblastoma |
| title_full | Immune Thrombocytopenia in a Child with Neuroblastoma |
| title_fullStr | Immune Thrombocytopenia in a Child with Neuroblastoma |
| title_full_unstemmed | Immune Thrombocytopenia in a Child with Neuroblastoma |
| title_short | Immune Thrombocytopenia in a Child with Neuroblastoma |
| title_sort | immune thrombocytopenia in a child with neuroblastoma |
| url | http://dx.doi.org/10.1155/2017/1329489 |
| work_keys_str_mv | AT hasantarkanikizoglu immunethrombocytopeniainachildwithneuroblastoma AT inciayan immunethrombocytopeniainachildwithneuroblastoma AT fatmatokat immunethrombocytopeniainachildwithneuroblastoma AT tulaytecimer immunethrombocytopeniainachildwithneuroblastoma AT goncatopuzlutekant immunethrombocytopeniainachildwithneuroblastoma |