Modified Rankin Scale at 90 Days Versus National Institutes of Health Stroke Scale at 24 Hours as Primary Outcome in Acute Stroke Trials

Background We investigate whether the National Institutes of Health Stroke Scale (NIHSS) at 24 hours could serve as a primary outcome in acute ischemic stroke trials, and whether combining 90‐day modified Rankin Scale (mRS) and 24‐hour NIHSS in a hierarchical outcome could enhance detection of treat...

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Main Authors:	Johanna M. Ospel, Scott Brown, Salome Bosshart, Alexander Stebner, Kazutaka Uchida, Andrew Demchuk, Jeffrey L. Saver, Philip White, Keith W. Muir, Diederik W. J. Dippel, Charles B. L. M. Majoie, Tudor G. Jovin, Bruce C. V. Campbell, Peter J. Mitchell, Serge Bracard, Francis Guillemin, Michael Hill, Mayank Goyal
Format:	Article
Language:	English
Published:	Wiley 2025-03-01
Series:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:	acute ischemic stroke endovascular treatment mRS NIHSS thrombectomy
Online Access:	https://www.ahajournals.org/doi/10.1161/JAHA.124.037752
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Modified Rankin Scale at 90 Days Versus National Institutes of Health Stroke Scale at 24 Hours as Primary Outcome in Acute Stroke Trials

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