Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention
Background. The relationship between fasting blood glucose (FBG) and microvascular obstruction (MVO) after primary percutaneous coronary intervention (PCI) remains unclear in nondiabetic patients with ST-segment elevation myocardial infarction (STEMI). This study aimed to determine the predictive va...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/8429218 |
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| author | Han Wu Ran Li Kun Wang Dan Mu Jian-Zhou Chen Xuan Wei Xue Bao Zhong-Hai Wei Jun Xie Biao Xu |
| author_facet | Han Wu Ran Li Kun Wang Dan Mu Jian-Zhou Chen Xuan Wei Xue Bao Zhong-Hai Wei Jun Xie Biao Xu |
| author_sort | Han Wu |
| collection | DOAJ |
| description | Background. The relationship between fasting blood glucose (FBG) and microvascular obstruction (MVO) after primary percutaneous coronary intervention (PCI) remains unclear in nondiabetic patients with ST-segment elevation myocardial infarction (STEMI). This study aimed to determine the predictive value of FBG in MVO in nondiabetic STEMI patients. Methods. A total of 108 nondiabetic STEMI patients undergoing primary PCI were enrolled in this study. The patients were classified into either the MVO group or non-MVO group based on cardiac magnetic resonance imaging (CMR). Results. FBG in the MVO group was higher than in the non-MVO group. Univariate analysis showed that FBG, peak high-sensitive troponin T (TnT), pre-PCI thrombolysis in myocardial infarction (pre-PCI TIMI) flow, left ventricular ejection fraction (LVEF), infarction size, left ventricular end-diastolic diameter (LVEDd), left ventricular end-diastolic volume (LVEDV), and global longitudinal strain (GLS) were likely predictive factors of MVO. After adjustment for other parameters, FBG, peak TnT, LVEF, and LVEDV remained independent predictors for MVO. Conclusion. FBG was independently associated with MVO in nondiabetic STEMI patients. |
| format | Article |
| id | doaj-art-0f3af6c8765944c0bb4c4e294864df15 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-0f3af6c8765944c0bb4c4e294864df152025-02-03T00:58:43ZengWileyCardiology Research and Practice2090-80162090-05972020-01-01202010.1155/2020/84292188429218Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary InterventionHan Wu0Ran Li1Kun Wang2Dan Mu3Jian-Zhou Chen4Xuan Wei5Xue Bao6Zhong-Hai Wei7Jun Xie8Biao Xu9Department of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Radiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaDepartment of Cardiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, ChinaBackground. The relationship between fasting blood glucose (FBG) and microvascular obstruction (MVO) after primary percutaneous coronary intervention (PCI) remains unclear in nondiabetic patients with ST-segment elevation myocardial infarction (STEMI). This study aimed to determine the predictive value of FBG in MVO in nondiabetic STEMI patients. Methods. A total of 108 nondiabetic STEMI patients undergoing primary PCI were enrolled in this study. The patients were classified into either the MVO group or non-MVO group based on cardiac magnetic resonance imaging (CMR). Results. FBG in the MVO group was higher than in the non-MVO group. Univariate analysis showed that FBG, peak high-sensitive troponin T (TnT), pre-PCI thrombolysis in myocardial infarction (pre-PCI TIMI) flow, left ventricular ejection fraction (LVEF), infarction size, left ventricular end-diastolic diameter (LVEDd), left ventricular end-diastolic volume (LVEDV), and global longitudinal strain (GLS) were likely predictive factors of MVO. After adjustment for other parameters, FBG, peak TnT, LVEF, and LVEDV remained independent predictors for MVO. Conclusion. FBG was independently associated with MVO in nondiabetic STEMI patients.http://dx.doi.org/10.1155/2020/8429218 |
| spellingShingle | Han Wu Ran Li Kun Wang Dan Mu Jian-Zhou Chen Xuan Wei Xue Bao Zhong-Hai Wei Jun Xie Biao Xu Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention Cardiology Research and Practice |
| title | Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention |
| title_full | Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention |
| title_fullStr | Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention |
| title_full_unstemmed | Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention |
| title_short | Predictive Value of Fasting Blood Glucose for Microvascular Obstruction in Nondiabetic Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention |
| title_sort | predictive value of fasting blood glucose for microvascular obstruction in nondiabetic patients with st segment elevation myocardial infarction after primary percutaneous coronary intervention |
| url | http://dx.doi.org/10.1155/2020/8429218 |
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