Brain-clinical biotyping in patients with idiopathic REM sleep behavior disorder

Brain-clinical biotyping in patients with idiopathic REM sleep behavior disorder

Abstract Idiopathic REM sleep behavior disorder (iRBD) is a prodromal stage of α-synucleinopathies including Parkinson’s disease (PD), yet its clinical heterogeneity remains underexplored. This study aimed to identify novel brain-clinical biotypes in iRBD by integrating structural MRI and clinical a...

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Main Authors: Shi Tang, Bei Huang, Yanlin Wang, Yaping Liu, Jing Wang, Li Zhou, Siyi Gong, Yuhua Yang, Joey WY Chan, Steven WH Chau, Winnie CW Chu, Jill Abrigo, Jean-François Gagnon, Yun Kwok Wing
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01012-0
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