Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence
Senescent cells secrete several molecules, collectively named senescence-associated secretory phenotype (SASP). In the SASP of cells that became senescent following several in vitro chemical and physical stress, we identified the IGFBP-4 protein that can be considered a general stress mediator. This...
Saved in:
Main Authors: | Nicola Alessio, Tiziana Squillaro, Giovanni Di Bernardo, Giovanni Galano, Roberto De Rosa, Mariarosa AB Melone, Gianfranco Peluso, Umberto Galderisi |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-03-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/54523 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Resolution of oncogene-induced senescence markers in HPV-infected cervical cancer tissue
by: Ashraf I. Khasawneh, et al.
Published: (2025-01-01) -
Plants and fungi metabolites as novel autophagy inducers and senescence inhibitors
by: Rivka Ofir
Published: (2024-07-01) -
The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities
by: Zehua Wang, et al.
Published: (2025-01-01) -
Cell culture expansion media choice affects secretory, protective and immuno-modulatory features of adipose mesenchymal stromal cell-derived secretomes for orthopaedic applications
by: Enrico Ragni, et al.
Published: (2025-03-01) -
Antimicrobial activity of adipose-derived mesenchymal stromal cell secretome against methicillin-resistant Staphylococcus aureus
by: Fatimah Shaaban, et al.
Published: (2025-01-01)