Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory cytokines/NF-KB signaling pathways

Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory cytokines/NF-KB signaling pathways

Introduction: Hypoxic-anoxic stress causes severe injury to the brain cells resulting in various neuropathological complications. Ginseng is widely used in Traditional Chinese Medicine (TCM) as a tonic for healthy living due to its adaptogenic/rejuvenating properties and in mitigating chronic stress...

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Main Authors: James Olukayode Oni, Divine Oluwaferanmi Oyenekan, Yetunde Olamide Olayemi, Osarugue Christabel Irabor, Precious Ogbuji, McCarthy Oritseweyinmi Tova, Paul Ademola Adeleke, Gbemisayo Adetomiwa Abbas, Solomon Umukoro
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Ginseng
Traditional Chinese medicine
Hypoxic-anoxic
Neurobehavioral deficits
Inflammatory/apoptotic
Antioxidant systems
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142525000077
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