Antibacterial Peptides from Plants: What They Are and How They Probably Work
Plant antibacterial peptides have been isolated from a wide variety of species. They consist of several protein groups with different features, such as the overall charge of the molecule, the content of disulphide bonds, and structural stability under environmental stress. Although the three-dimensi...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Biochemistry Research International |
| Online Access: | http://dx.doi.org/10.1155/2011/250349 |
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| author | Patrícia Barbosa Pelegrini Rafael Perseghini del Sarto Osmar Nascimento Silva Octávio Luiz Franco Maria Fátima Grossi-de-Sa |
| author_facet | Patrícia Barbosa Pelegrini Rafael Perseghini del Sarto Osmar Nascimento Silva Octávio Luiz Franco Maria Fátima Grossi-de-Sa |
| author_sort | Patrícia Barbosa Pelegrini |
| collection | DOAJ |
| description | Plant antibacterial peptides have been isolated from a wide variety of species. They consist of several protein groups with different features, such as the overall charge of the molecule, the content of disulphide bonds, and structural stability under environmental stress. Although the three-dimensional structures of several classes of plant peptides are well determined, the mechanism of action of some of these molecules is still not well defined. However, further studies may provide new evidences for their function on bacterial cell wall. Therefore, this paper focuses on plant peptides that show activity against plant-pathogenic and human-pathogenic bacteria. Furthermore, we describe the folding of several peptides and similarities among their three-dimensional structures. Some hypotheses for their mechanisms of action and attack on the bacterial membrane surface are also proposed. |
| format | Article |
| id | doaj-art-0eedaaad359b4ef284350c7229f2dde0 |
| institution | Kabale University |
| issn | 2090-2247 2090-2255 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Biochemistry Research International |
| spelling | doaj-art-0eedaaad359b4ef284350c7229f2dde02025-02-03T05:46:54ZengWileyBiochemistry Research International2090-22472090-22552011-01-01201110.1155/2011/250349250349Antibacterial Peptides from Plants: What They Are and How They Probably WorkPatrícia Barbosa Pelegrini0Rafael Perseghini del Sarto1Osmar Nascimento Silva2Octávio Luiz Franco3Maria Fátima Grossi-de-Sa4Laboratorio de Interação Molecular Planta-Praga I, Embrapa Recursos Genéticos e Biotecnologia, 70770-197 DF, BrazilLaboratorio de Interação Molecular Planta-Praga I, Embrapa Recursos Genéticos e Biotecnologia, 70770-197 DF, BrazilCentro de Analises Proteômicas e Bioquímicas, Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, 70790-160 DF, BrazilCentro de Analises Proteômicas e Bioquímicas, Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, 70790-160 DF, BrazilLaboratorio de Interação Molecular Planta-Praga I, Embrapa Recursos Genéticos e Biotecnologia, 70770-197 DF, BrazilPlant antibacterial peptides have been isolated from a wide variety of species. They consist of several protein groups with different features, such as the overall charge of the molecule, the content of disulphide bonds, and structural stability under environmental stress. Although the three-dimensional structures of several classes of plant peptides are well determined, the mechanism of action of some of these molecules is still not well defined. However, further studies may provide new evidences for their function on bacterial cell wall. Therefore, this paper focuses on plant peptides that show activity against plant-pathogenic and human-pathogenic bacteria. Furthermore, we describe the folding of several peptides and similarities among their three-dimensional structures. Some hypotheses for their mechanisms of action and attack on the bacterial membrane surface are also proposed.http://dx.doi.org/10.1155/2011/250349 |
| spellingShingle | Patrícia Barbosa Pelegrini Rafael Perseghini del Sarto Osmar Nascimento Silva Octávio Luiz Franco Maria Fátima Grossi-de-Sa Antibacterial Peptides from Plants: What They Are and How They Probably Work Biochemistry Research International |
| title | Antibacterial Peptides from Plants: What They Are and How They Probably Work |
| title_full | Antibacterial Peptides from Plants: What They Are and How They Probably Work |
| title_fullStr | Antibacterial Peptides from Plants: What They Are and How They Probably Work |
| title_full_unstemmed | Antibacterial Peptides from Plants: What They Are and How They Probably Work |
| title_short | Antibacterial Peptides from Plants: What They Are and How They Probably Work |
| title_sort | antibacterial peptides from plants what they are and how they probably work |
| url | http://dx.doi.org/10.1155/2011/250349 |
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