Papain Affects the Percentage and Morphology of Microglia in Hippocampal Neuron–Glial Cultures

Papain Affects the Percentage and Morphology of Microglia in Hippocampal Neuron–Glial Cultures

<b>Background.</b> Microglia, accounting for 5–15% of total brain cells, represent an essential population of glial cells in the cultures used for modeling neuroinflammation in vitro. However, microglia proliferation is poor in neuron–glial cultures. Here, we studied the population compo...

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Bibliographic Details
Main Authors: Ivan A. Tumozov, Valentina N. Mal’tseva, Sergei A. Maiorov, Artem M. Kosenkov, Sergei G. Gaidin
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Brain Sciences
Subjects:
microglia
triculture
papain
CDr20
intracellular Ca<sup>2+</sup> concentration
Iba1
Online Access:https://www.mdpi.com/2076-3425/15/5/442
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