Integrating bioinformatics with experimental validation unveils immunological and prognostic significance of PVRIG in pan-cancer

Abstract The poliovirus receptor-related immunoglobulin domain-containing protein (PVRIG) is a recently identified immune checkpoint receptor predominantly expressed on natural killer and CD8 + T cells. This study investigated the role of PVRIG in the tumor immune microenvironment and its prognostic...

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Bibliographic Details
Main Authors: Peng Ma, Ruichen Zhang, Weili Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-89308-2
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