Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree

Introduction Every year 2.4 million deaths occur worldwide in babies younger than 28 days. Approximately 70% of these deaths occur in low-resource settings because of failure to implement evidence-based interventions. Digital health technologies may offer an implementation solution. Since 2014, we h...

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Main Authors: Hassan Haghparast-Bidgoli, Michelle Heys, Caroline Crehan, Erin Kesler, Monica Lakhanpaul, Emma Wilson, Fabiana Lorencatto, Felicity Fitzgerald, Mario Cortina Borja, Msandeni Chiume, Hannah Gannon, Simbarashe Chimhuya, Gwendoline Chimhini, Tim Hull-Bailey, Tarisai Chiyaka, Yali Sassoon, Deliwe Nkhoma, Nushrat Khan, Alexander G. Stevenson, Kristina Curtis
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/7/e056605.full
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author Hassan Haghparast-Bidgoli
Michelle Heys
Caroline Crehan
Erin Kesler
Monica Lakhanpaul
Emma Wilson
Fabiana Lorencatto
Felicity Fitzgerald
Mario Cortina Borja
Msandeni Chiume
Hannah Gannon
Simbarashe Chimhuya
Gwendoline Chimhini
Tim Hull-Bailey
Tarisai Chiyaka
Yali Sassoon
Deliwe Nkhoma
Nushrat Khan
Alexander G. Stevenson
Kristina Curtis
author_facet Hassan Haghparast-Bidgoli
Michelle Heys
Caroline Crehan
Erin Kesler
Monica Lakhanpaul
Emma Wilson
Fabiana Lorencatto
Felicity Fitzgerald
Mario Cortina Borja
Msandeni Chiume
Hannah Gannon
Simbarashe Chimhuya
Gwendoline Chimhini
Tim Hull-Bailey
Tarisai Chiyaka
Yali Sassoon
Deliwe Nkhoma
Nushrat Khan
Alexander G. Stevenson
Kristina Curtis
author_sort Hassan Haghparast-Bidgoli
collection DOAJ
description Introduction Every year 2.4 million deaths occur worldwide in babies younger than 28 days. Approximately 70% of these deaths occur in low-resource settings because of failure to implement evidence-based interventions. Digital health technologies may offer an implementation solution. Since 2014, we have worked in Bangladesh, Malawi, Zimbabwe and the UK to develop and pilot Neotree: an android app with accompanying data visualisation, linkage and export. Its low-cost hardware and state-of-the-art software are used to improve bedside postnatal care and to provide insights into population health trends, to impact wider policy and practice.Methods and analysis This is a mixed methods (1) intervention codevelopment and optimisation and (2) pilot implementation evaluation (including economic evaluation) study. Neotree will be implemented in two hospitals in Zimbabwe, and one in Malawi. Over the 2-year study period clinical and demographic newborn data will be collected via Neotree, in addition to behavioural science informed qualitative and quantitative implementation evaluation and measures of cost, newborn care quality and usability. Neotree clinical decision support algorithms will be optimised according to best available evidence and clinical validation studies.Ethics and dissemination This is a Wellcome Trust funded project (215742_Z_19_Z). Research ethics approvals have been obtained: Malawi College of Medicine Research and Ethics Committee (P.01/20/2909; P.02/19/2613); UCL (17123/001, 6681/001, 5019/004); Medical Research Council Zimbabwe (MRCZ/A/2570), BRTI and JREC institutional review boards (AP155/2020; JREC/327/19), Sally Mugabe Hospital Ethics Committee (071119/64; 250418/48). Results will be disseminated via academic publications and public and policy engagement activities. In this study, the care for an estimated 15 000 babies across three sites will be impacted.Trial registration number NCT0512707; Pre-results
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spelling doaj-art-0ede992568a546ee8bf9f47b1f06f9722025-01-31T07:10:11ZengBMJ Publishing GroupBMJ Open2044-60552022-07-0112710.1136/bmjopen-2021-056605Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: NeotreeHassan Haghparast-Bidgoli0Michelle Heys1Caroline Crehan2Erin Kesler3Monica Lakhanpaul4Emma Wilson5Fabiana Lorencatto6Felicity Fitzgerald7Mario Cortina Borja8Msandeni Chiume9Hannah Gannon10Simbarashe Chimhuya11Gwendoline Chimhini12Tim Hull-Bailey13Tarisai Chiyaka14Yali Sassoon15Deliwe Nkhoma16Nushrat Khan17Alexander G. Stevenson18Kristina Curtis19UCL Institute for Global Health, London, UKDepartment of Population, Policy & Practice, UCL Great Ormond Street Institute of Child Health, London, UKPopulation, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UKThe Children`s Hospital of Philadelphia, Philadelphia, Pennsylvania, USAUCL Great Ormond Street Institute of Child Health, University College London (UCL), UKPopulation, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UKEpidemiology and Public Health, UCL, London, UKImperial College London, London, UKPopulation, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UKDepartment of Pediatrics, Kamuzu Central Hospital, Lilongwe, MalawiPopulation, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UKUnit of Child and Adolescent Health, Faculty of Medicine and Health Sciences, University of Zimbabwe, Harare, Zimbabwe4Unit of Child and Adolescent Health, Primary Healthcare Sciences, University of ZimbabwePopulation, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UKCentre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, Harare, ZimbabweSnowplow Analytics, London, UKParent and Child Health Initiative Trust, Lilongwe, Central Region, MalawiPopulation, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UKMbuya Nehanda Maternity Hospital, Harare, ZimbabweUCL Centre for Behaviour Change, London, UKIntroduction Every year 2.4 million deaths occur worldwide in babies younger than 28 days. Approximately 70% of these deaths occur in low-resource settings because of failure to implement evidence-based interventions. Digital health technologies may offer an implementation solution. Since 2014, we have worked in Bangladesh, Malawi, Zimbabwe and the UK to develop and pilot Neotree: an android app with accompanying data visualisation, linkage and export. Its low-cost hardware and state-of-the-art software are used to improve bedside postnatal care and to provide insights into population health trends, to impact wider policy and practice.Methods and analysis This is a mixed methods (1) intervention codevelopment and optimisation and (2) pilot implementation evaluation (including economic evaluation) study. Neotree will be implemented in two hospitals in Zimbabwe, and one in Malawi. Over the 2-year study period clinical and demographic newborn data will be collected via Neotree, in addition to behavioural science informed qualitative and quantitative implementation evaluation and measures of cost, newborn care quality and usability. Neotree clinical decision support algorithms will be optimised according to best available evidence and clinical validation studies.Ethics and dissemination This is a Wellcome Trust funded project (215742_Z_19_Z). Research ethics approvals have been obtained: Malawi College of Medicine Research and Ethics Committee (P.01/20/2909; P.02/19/2613); UCL (17123/001, 6681/001, 5019/004); Medical Research Council Zimbabwe (MRCZ/A/2570), BRTI and JREC institutional review boards (AP155/2020; JREC/327/19), Sally Mugabe Hospital Ethics Committee (071119/64; 250418/48). Results will be disseminated via academic publications and public and policy engagement activities. In this study, the care for an estimated 15 000 babies across three sites will be impacted.Trial registration number NCT0512707; Pre-resultshttps://bmjopen.bmj.com/content/12/7/e056605.full
spellingShingle Hassan Haghparast-Bidgoli
Michelle Heys
Caroline Crehan
Erin Kesler
Monica Lakhanpaul
Emma Wilson
Fabiana Lorencatto
Felicity Fitzgerald
Mario Cortina Borja
Msandeni Chiume
Hannah Gannon
Simbarashe Chimhuya
Gwendoline Chimhini
Tim Hull-Bailey
Tarisai Chiyaka
Yali Sassoon
Deliwe Nkhoma
Nushrat Khan
Alexander G. Stevenson
Kristina Curtis
Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree
BMJ Open
title Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree
title_full Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree
title_fullStr Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree
title_full_unstemmed Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree
title_short Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree
title_sort protocol for an intervention development and pilot implementation evaluation study of an e health solution to improve newborn care quality and survival in two low resource settings malawi and zimbabwe neotree
url https://bmjopen.bmj.com/content/12/7/e056605.full
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