Protective IgM-mediated immunity against Vibrio anguillarum in Atlantic cod with evolutionary losses of mhc class II and cd4

Protective IgM-mediated immunity against Vibrio anguillarum in Atlantic cod with evolutionary losses of mhc class II and cd4

The unique adaptive immune system of the Atlantic cod (Gadus morhua), with genetic loss of the mhc class II and cd4, poses questions about the protective role of specific antibodies in this species. We investigate the IgM response against Vibrio anguillarum, a common pathogen in aquaculture. Juvenil...

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Bibliographic Details
Main Authors: Alexandra Jonsson, Adrián López-Porras, Simen Foyn Nørstebø, Naomi Croft Guslund, Henning Sørum, Shuo-Wang Qiao, Finn-Eirik Johansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
Atlantic cod
Vibrio anguillarum
IgM antibodies
antibody response
adaptive immunity
aquaculture
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1579541/full
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