Role of Copper and Zinc Ions in the Hydrolytic Degradation of Neurodegeneration-Related Peptides

Spontaneous cleavage reactions normally occur in vivo on amino acid peptide backbones, leading to fragmentation products that can have different physiological roles and toxicity, particularly when the substrate of the hydrolytic processes are neuronal peptides and proteins highly related to neurodeg...

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Bibliographic Details
Main Authors: Valentina Pirota, Enrico Monzani, Simone Dell’Acqua, Chiara Bacchella
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/2/363
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