Safety assessment of laronidase: real-world adverse event analysis based on the FDA adverse event reporting system (FAERS)

Safety assessment of laronidase: real-world adverse event analysis based on the FDA adverse event reporting system (FAERS)

ObjectiveLaronidase is the first drug of enzyme replacement therapy approved for the treatment of mucopolysaccharidosis type I (MPS I). However, its adverse events (AEs) have not been investigated in real - world settings. The aim of this study was to investigate AEs associated with laronidase using...

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Bibliographic Details
Main Authors:	Zhuomiao Lin, Junling Xue, Meiqing Yang, Xihui Yu, Jiahong Zhong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Pharmacology
Subjects:	laronidase FAERS adverse events mucopolysaccharidosis type I pharmacovigilance
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1623921/full
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