Uncertainty-aware traction force microscopy.

Traction Force Microscopy (TFM) is a versatile tool to quantify cell-exerted forces by imaging and tracking fiduciary markers embedded in elastic substrates. The computations involved in TFM are often ill-conditioned, and data smoothing or regularization is required to avoid overfitting the noise in...

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Bibliographic Details
Main Authors: Adithan Kandasamy, Yi-Ting Yeh, Ricardo Serrano, Mark Mercola, Juan C Del Alamo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013079
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