Permissive immunosuppression facilitates the expansion of ex vivo administered regulatory T cells in the lung allograft
Abstract In lung transplantation (LT), alloreactive T cell priming begins in the graft, a process that can be inhibited by seeding the graft with recipient-derived expanded polyclonal regulatory T cells (Tregs) using ex vivo lung perfusion (EVLP) prior to transplantation. However, this therapy alone...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-06835-8 |
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