Influence of Physical Activity and Nutrition on Obesity-Related Immune Function
Research examining immune function during obesity suggests that excessive adiposity is linked to impaired immune responses leading to pathology. The deleterious effects of obesity on immunity have been associated with the systemic proinflammatory profile generated by the secretory molecules derived...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/752071 |
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| author | Chun-Jung Huang Michael C. Zourdos Edward Jo Michael J. Ormsbee |
| author_facet | Chun-Jung Huang Michael C. Zourdos Edward Jo Michael J. Ormsbee |
| author_sort | Chun-Jung Huang |
| collection | DOAJ |
| description | Research examining immune function during obesity suggests that excessive adiposity is linked to impaired immune responses leading to pathology. The deleterious effects of obesity on immunity have been associated with the systemic proinflammatory profile generated by the secretory molecules derived from adipose cells. These include inflammatory peptides, such as TNF-α, CRP, and IL-6. Consequently, obesity is now characterized as a state of chronic low-grade systemic inflammation, a condition considerably linked to the development of comorbidity. Given the critical role of adipose tissue in the inflammatory process, especially in obese individuals, it becomes an important clinical objective to identify lifestyle factors that may affect the obesity-immune system relationship. For instance, stress, physical activity, and nutrition have each shown to be a significant lifestyle factor influencing the inflammatory profile associated with the state of obesity. Therefore, the purpose of this review is to comprehensively evaluate the impact of lifestyle factors, in particular psychological stress, physical activity, and nutrition, on obesity-related immune function with specific focus on inflammation. |
| format | Article |
| id | doaj-art-0e418567320e473ab0696cf3d2099775 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-0e418567320e473ab0696cf3d20997752025-02-03T06:11:48ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/752071752071Influence of Physical Activity and Nutrition on Obesity-Related Immune FunctionChun-Jung Huang0Michael C. Zourdos1Edward Jo2Michael J. Ormsbee3Department of Exercise Science and Health Promotion, Florida Atlantic University, 777 Glades Road, FH11A-126B, Boca Raton, FL 33431, USADepartment of Exercise Science and Health Promotion, Florida Atlantic University, 777 Glades Road, FH11A-126B, Boca Raton, FL 33431, USADepartment of Kinesiology and Health Promotion, California State Polytechnic University, Pomona, Pomona, CA, USADepartment of Nutrition, Food and Exercise Sciences, The Florida State University, Tallahassee, FL, USAResearch examining immune function during obesity suggests that excessive adiposity is linked to impaired immune responses leading to pathology. The deleterious effects of obesity on immunity have been associated with the systemic proinflammatory profile generated by the secretory molecules derived from adipose cells. These include inflammatory peptides, such as TNF-α, CRP, and IL-6. Consequently, obesity is now characterized as a state of chronic low-grade systemic inflammation, a condition considerably linked to the development of comorbidity. Given the critical role of adipose tissue in the inflammatory process, especially in obese individuals, it becomes an important clinical objective to identify lifestyle factors that may affect the obesity-immune system relationship. For instance, stress, physical activity, and nutrition have each shown to be a significant lifestyle factor influencing the inflammatory profile associated with the state of obesity. Therefore, the purpose of this review is to comprehensively evaluate the impact of lifestyle factors, in particular psychological stress, physical activity, and nutrition, on obesity-related immune function with specific focus on inflammation.http://dx.doi.org/10.1155/2013/752071 |
| spellingShingle | Chun-Jung Huang Michael C. Zourdos Edward Jo Michael J. Ormsbee Influence of Physical Activity and Nutrition on Obesity-Related Immune Function The Scientific World Journal |
| title | Influence of Physical Activity and Nutrition on Obesity-Related Immune Function |
| title_full | Influence of Physical Activity and Nutrition on Obesity-Related Immune Function |
| title_fullStr | Influence of Physical Activity and Nutrition on Obesity-Related Immune Function |
| title_full_unstemmed | Influence of Physical Activity and Nutrition on Obesity-Related Immune Function |
| title_short | Influence of Physical Activity and Nutrition on Obesity-Related Immune Function |
| title_sort | influence of physical activity and nutrition on obesity related immune function |
| url | http://dx.doi.org/10.1155/2013/752071 |
| work_keys_str_mv | AT chunjunghuang influenceofphysicalactivityandnutritiononobesityrelatedimmunefunction AT michaelczourdos influenceofphysicalactivityandnutritiononobesityrelatedimmunefunction AT edwardjo influenceofphysicalactivityandnutritiononobesityrelatedimmunefunction AT michaeljormsbee influenceofphysicalactivityandnutritiononobesityrelatedimmunefunction |