The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy

Objective. We aimed to investigate the effect of peritubal local anesthetic and opioid infiltration on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy. Material and Methods. Patients aged between 18 and 65 years and ASA I-III were included in this double-...

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Main Authors: Isra Karaduman, Derya Karasu, Canan Yilmaz, Sedat Oner, Hilal Erdem Solak, Gulsen Korfali
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2017/2454267
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author Isra Karaduman
Derya Karasu
Canan Yilmaz
Sedat Oner
Hilal Erdem Solak
Gulsen Korfali
author_facet Isra Karaduman
Derya Karasu
Canan Yilmaz
Sedat Oner
Hilal Erdem Solak
Gulsen Korfali
author_sort Isra Karaduman
collection DOAJ
description Objective. We aimed to investigate the effect of peritubal local anesthetic and opioid infiltration on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy. Material and Methods. Patients aged between 18 and 65 years and ASA I-III were included in this double-blind, randomized study. The patients were divided into two groups. All patients underwent spinoepidural anesthesia. 20 mL of 0.25 percent bupivacaine + 5 mg morphine (0.5 mL), in Group P (n=66), infiltrated the renal capsule, perinephric fat, muscles, subcutaneous tissue, and skin under fluoroscopy. In Group C (n=64), none of the patients received a peritubal injection. In the first 24 h pain scores, time of the first analgesic demand, the mean number of analgesic demands, and postoperative complications were compared between groups. Results. The mean VAS score at postoperative 8, 12, and 24 h and dynamic VAS score at postoperative 4, 8, 12, and 24 h were significantly lower in Group P. VAS score at postoperative 4 h was not significant. Time of the first analgesic demand was significantly longer in Group P. Conclusion. Our study results suggest that peritubal infiltration of bupivacaine with morphine after percutaneous nephrolithotomy is an effective method for postoperative pain control and reduces analgesic consumption.
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spelling doaj-art-0e40081d5ac24a32b6a99d8a9e4e3b4b2025-02-03T06:42:20ZengWileyPain Research and Management1203-67651918-15232017-01-01201710.1155/2017/24542672454267The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous NephrolithotomyIsra Karaduman0Derya Karasu1Canan Yilmaz2Sedat Oner3Hilal Erdem Solak4Gulsen Korfali5Bursa Yuksek Ihtisas Training and Education Hospital, Clinic of Anesthesiology and Reanimation, Bursa, TurkeyBursa Yuksek Ihtisas Training and Education Hospital, Clinic of Anesthesiology and Reanimation, Bursa, TurkeyBursa Yuksek Ihtisas Training and Education Hospital, Clinic of Anesthesiology and Reanimation, Bursa, TurkeyBursa Yuksek Ihtisas Training and Education Hospital, Urology Clinic, Bursa, TurkeyBursa Yuksek Ihtisas Training and Education Hospital, Clinic of Anesthesiology and Reanimation, Bursa, TurkeyBursa Yuksek Ihtisas Training and Education Hospital, Clinic of Anesthesiology and Reanimation, Bursa, TurkeyObjective. We aimed to investigate the effect of peritubal local anesthetic and opioid infiltration on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy. Material and Methods. Patients aged between 18 and 65 years and ASA I-III were included in this double-blind, randomized study. The patients were divided into two groups. All patients underwent spinoepidural anesthesia. 20 mL of 0.25 percent bupivacaine + 5 mg morphine (0.5 mL), in Group P (n=66), infiltrated the renal capsule, perinephric fat, muscles, subcutaneous tissue, and skin under fluoroscopy. In Group C (n=64), none of the patients received a peritubal injection. In the first 24 h pain scores, time of the first analgesic demand, the mean number of analgesic demands, and postoperative complications were compared between groups. Results. The mean VAS score at postoperative 8, 12, and 24 h and dynamic VAS score at postoperative 4, 8, 12, and 24 h were significantly lower in Group P. VAS score at postoperative 4 h was not significant. Time of the first analgesic demand was significantly longer in Group P. Conclusion. Our study results suggest that peritubal infiltration of bupivacaine with morphine after percutaneous nephrolithotomy is an effective method for postoperative pain control and reduces analgesic consumption.http://dx.doi.org/10.1155/2017/2454267
spellingShingle Isra Karaduman
Derya Karasu
Canan Yilmaz
Sedat Oner
Hilal Erdem Solak
Gulsen Korfali
The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
Pain Research and Management
title The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
title_full The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
title_fullStr The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
title_full_unstemmed The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
title_short The Effect of Peritubal Infiltration with Bupivacaine and Morphine on Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
title_sort effect of peritubal infiltration with bupivacaine and morphine on postoperative analgesia in patients undergoing percutaneous nephrolithotomy
url http://dx.doi.org/10.1155/2017/2454267
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