A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial
Abstract Objectives To evaluate central quadrantectomy and nipple resection with areola preservation (CQ-NR-AP) as a new reconstructive oncoplastic technique Versus Grisotti flap mammoplasty (GFM) in central malignant tumors of the breast extending to the nipple, in terms of time procedures, breast...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-01-01
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| Series: | Journal of the Egyptian National Cancer Institute |
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| Online Access: | https://doi.org/10.1186/s43046-024-00253-z |
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| author | Philobater Bahgat Adly Awad Basma Hussein Abdelaziz Hassan Abanoub Adel Shafek Awad Abdelrahman Ahmed Younis Mohamed Attaia Kerolos Bahgat Adly Awad Dina Mohamed Hanafy Ahmed Gamal El Din Osman |
| author_facet | Philobater Bahgat Adly Awad Basma Hussein Abdelaziz Hassan Abanoub Adel Shafek Awad Abdelrahman Ahmed Younis Mohamed Attaia Kerolos Bahgat Adly Awad Dina Mohamed Hanafy Ahmed Gamal El Din Osman |
| author_sort | Philobater Bahgat Adly Awad |
| collection | DOAJ |
| description | Abstract Objectives To evaluate central quadrantectomy and nipple resection with areola preservation (CQ-NR-AP) as a new reconstructive oncoplastic technique Versus Grisotti flap mammoplasty (GFM) in central malignant tumors of the breast extending to the nipple, in terms of time procedures, breast symmetry, patient satisfaction, postoperative complications, and local recurrence. Patients and methods The current study is a single-blind, single-center, randomized, controlled trial that was performed between May 2018 and May 2023 in the breast surgery unit of University Hospitals. This trial involved 40 individuals who had central breast lesions that extended to the nipple and were monitored for two years following surgery. Results As regards the mean intra-operative time in minutes, in the group (I) was 80.1 with a standard deviation of ± 13.9, and ingroup (II) was 138.9 with a standard deviation of ± 14.02 (p = 0.001). The seroma was detected in zero cases in group (I) and 2(10%) cases in group II (p = 0.487) and those two cases were managed by aspiration only. Regarding, the wound infection was found in one case (5%) in group (I) and 3(15%) cases in group II (p = 0.605). Regarding patient satisfaction and breast, symmetry was much better in the group (I). Conclusion The safety and ease of central quadrantectomy and nipple resection with areola preservation were demonstrated in a two-year follow-up, with a lower incidence of complications compared to the Grisotti flap mammoplasty technique. Furthermore, this approach was associated with higher patient satisfaction, which is a significant achievement in the management of centrally located breast tumors. Trial registration PACTR202405688323721. 28/05/2024. |
| format | Article |
| id | doaj-art-0dfb35009eff4628b29f2f3c2f7897e0 |
| institution | Kabale University |
| issn | 2589-0409 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Journal of the Egyptian National Cancer Institute |
| spelling | doaj-art-0dfb35009eff4628b29f2f3c2f7897e02025-01-26T12:47:55ZengSpringerOpenJournal of the Egyptian National Cancer Institute2589-04092025-01-013711910.1186/s43046-024-00253-zA comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trialPhilobater Bahgat Adly Awad0Basma Hussein Abdelaziz Hassan1Abanoub Adel Shafek Awad2Abdelrahman Ahmed Younis Mohamed Attaia3Kerolos Bahgat Adly Awad4Dina Mohamed Hanafy5Ahmed Gamal El Din Osman6General Surgery Department, Faculty of Medicine, Ain Shams UniversityGeneral Surgery Department, Faculty of Medicine, Ain Shams UniversityGeneral Surgery Department, Faculty of Medicine, Ain Shams UniversityGeneral Surgery Department, Faculty of Medicine, Ain Shams UniversityGeneral Surgery Department, Faculty of Medicine, Ain Shams UniversityGeneral Surgery Department, Faculty of Medicine, Ain Shams UniversityGeneral Surgery Department, Faculty of Medicine, Ain Shams UniversityAbstract Objectives To evaluate central quadrantectomy and nipple resection with areola preservation (CQ-NR-AP) as a new reconstructive oncoplastic technique Versus Grisotti flap mammoplasty (GFM) in central malignant tumors of the breast extending to the nipple, in terms of time procedures, breast symmetry, patient satisfaction, postoperative complications, and local recurrence. Patients and methods The current study is a single-blind, single-center, randomized, controlled trial that was performed between May 2018 and May 2023 in the breast surgery unit of University Hospitals. This trial involved 40 individuals who had central breast lesions that extended to the nipple and were monitored for two years following surgery. Results As regards the mean intra-operative time in minutes, in the group (I) was 80.1 with a standard deviation of ± 13.9, and ingroup (II) was 138.9 with a standard deviation of ± 14.02 (p = 0.001). The seroma was detected in zero cases in group (I) and 2(10%) cases in group II (p = 0.487) and those two cases were managed by aspiration only. Regarding, the wound infection was found in one case (5%) in group (I) and 3(15%) cases in group II (p = 0.605). Regarding patient satisfaction and breast, symmetry was much better in the group (I). Conclusion The safety and ease of central quadrantectomy and nipple resection with areola preservation were demonstrated in a two-year follow-up, with a lower incidence of complications compared to the Grisotti flap mammoplasty technique. Furthermore, this approach was associated with higher patient satisfaction, which is a significant achievement in the management of centrally located breast tumors. Trial registration PACTR202405688323721. 28/05/2024.https://doi.org/10.1186/s43046-024-00253-zBreast cancerOncoplastic breast surgeryGrisotti flapMammoplastyCentral breast tumorsGrisotti technique |
| spellingShingle | Philobater Bahgat Adly Awad Basma Hussein Abdelaziz Hassan Abanoub Adel Shafek Awad Abdelrahman Ahmed Younis Mohamed Attaia Kerolos Bahgat Adly Awad Dina Mohamed Hanafy Ahmed Gamal El Din Osman A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial Journal of the Egyptian National Cancer Institute Breast cancer Oncoplastic breast surgery Grisotti flap Mammoplasty Central breast tumors Grisotti technique |
| title | A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial |
| title_full | A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial |
| title_fullStr | A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial |
| title_full_unstemmed | A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial |
| title_short | A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial |
| title_sort | comparative study between central quadrantectomy and nipple resection with areola preservation versus grisotti flap mammoplasty in central breast lesions extending to nipple a randomized clinical trial |
| topic | Breast cancer Oncoplastic breast surgery Grisotti flap Mammoplasty Central breast tumors Grisotti technique |
| url | https://doi.org/10.1186/s43046-024-00253-z |
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