Crohn's Disease Defined in Three Elderly Disters
Three elderly sisters presented with symptomatic Crohn's disease. All had ileocolic involvement, and granulomatous inflammation was documented in endoscopic biopsies or surgically resected intestinal specimens. The present report documents the unusual occurrence of very late phenotypical expres...
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| Format: | Article |
| Language: | English |
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Wiley
2005-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2005/241486 |
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| _version_ | 1832548751879700480 |
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| author | Hugh J Freeman |
| author_facet | Hugh J Freeman |
| author_sort | Hugh J Freeman |
| collection | DOAJ |
| description | Three elderly sisters presented with symptomatic Crohn's disease. All had ileocolic involvement, and granulomatous inflammation was documented in endoscopic biopsies or surgically resected intestinal specimens. The present report documents the unusual occurrence of very late phenotypical expression of familial ileocolic Crohn's disease. The observations presented here reflect a possible gene-based predisposition to Crohn's disease or, alternatively, disease clustering related to a commonly shared environmental factor. |
| format | Article |
| id | doaj-art-0dcb73eb686144ca95742109bdb10033 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-0dcb73eb686144ca95742109bdb100332025-02-03T06:13:10ZengWileyCanadian Journal of Gastroenterology0835-79002005-01-0119425125210.1155/2005/241486Crohn's Disease Defined in Three Elderly DistersHugh J Freeman0Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, British Columbia, CanadaThree elderly sisters presented with symptomatic Crohn's disease. All had ileocolic involvement, and granulomatous inflammation was documented in endoscopic biopsies or surgically resected intestinal specimens. The present report documents the unusual occurrence of very late phenotypical expression of familial ileocolic Crohn's disease. The observations presented here reflect a possible gene-based predisposition to Crohn's disease or, alternatively, disease clustering related to a commonly shared environmental factor.http://dx.doi.org/10.1155/2005/241486 |
| spellingShingle | Hugh J Freeman Crohn's Disease Defined in Three Elderly Disters Canadian Journal of Gastroenterology |
| title | Crohn's Disease Defined in Three Elderly Disters |
| title_full | Crohn's Disease Defined in Three Elderly Disters |
| title_fullStr | Crohn's Disease Defined in Three Elderly Disters |
| title_full_unstemmed | Crohn's Disease Defined in Three Elderly Disters |
| title_short | Crohn's Disease Defined in Three Elderly Disters |
| title_sort | crohn s disease defined in three elderly disters |
| url | http://dx.doi.org/10.1155/2005/241486 |
| work_keys_str_mv | AT hughjfreeman crohnsdiseasedefinedinthreeelderlydisters |