Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity

SARS-CoV-2, a lung-damaging virus, is what causes COVID-19. While a decline in lymphocyte counts suggests immune system harm, a rise in neutrophil counts reflects the severity of the inflammatory response. A high NLR value results from an increase in neutrophils and a decrease in lymphocytes. On the...

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Main Authors: Citra Suhesty, Wimba Widagdho Dinutanayo, Maria Tuntun, Hidayat Hidayat
Format: Article
Language:Indonesian
Published: Politeknik Kesehatan Tanjung Karang 2023-09-01
Series:Jurnal Kesehatan
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Online Access:https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/3775
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author Citra Suhesty
Wimba Widagdho Dinutanayo
Maria Tuntun
Hidayat Hidayat
author_facet Citra Suhesty
Wimba Widagdho Dinutanayo
Maria Tuntun
Hidayat Hidayat
author_sort Citra Suhesty
collection DOAJ
description SARS-CoV-2, a lung-damaging virus, is what causes COVID-19. While a decline in lymphocyte counts suggests immune system harm, a rise in neutrophil counts reflects the severity of the inflammatory response. A high NLR value results from an increase in neutrophils and a decrease in lymphocytes. On the other hand, when plasmin breaks down fibrin to dissolve blood clots, it creates pieces called D-dimers. ARDS is predicted by an elevated D-dimer level. The study's objective was to ascertain how the severity of COVID-19 patients at Dr. H. Abdul Moeloek in 2021 related to NLR and D-dimer levels. Analytical research with a retrospective design is being conducted. The Rank Spearman correlation test and Pearson Chi-Square analyzed medical record data for COVID-19 patients. The study was carried out in Dr. H. Abdul Moeloek in June 2022. 205 COVID-19 patients who underwent NLR and D-dimer testing and were categorized based on the severity of the condition served as the study's subjects. The test findings revealed a substantial connection between NLR and D-dimer (r=0.583), demonstrating a strong and favorable link. NLR and illness severity showed a significant relationship (r=0.49). D-dimer and illness severity also showed a strong connection (r=0.51).
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institution Kabale University
issn 2086-7751
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language Indonesian
publishDate 2023-09-01
publisher Politeknik Kesehatan Tanjung Karang
record_format Article
series Jurnal Kesehatan
spelling doaj-art-0dc4bc3484c14466b00631ce38c935022025-01-22T14:04:07ZindPoliteknik Kesehatan Tanjung KarangJurnal Kesehatan2086-77512548-56952023-09-0114238238710.26630/jk.v14i2.37753169Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 SeverityCitra Suhesty0Wimba Widagdho Dinutanayo1Maria Tuntun2Hidayat Hidayat3Poltekkes TanjungkarangPoltekkes TanjungkarangPoltekkes TanjungkarangRSUD Dr. H. Abdul MoeloekSARS-CoV-2, a lung-damaging virus, is what causes COVID-19. While a decline in lymphocyte counts suggests immune system harm, a rise in neutrophil counts reflects the severity of the inflammatory response. A high NLR value results from an increase in neutrophils and a decrease in lymphocytes. On the other hand, when plasmin breaks down fibrin to dissolve blood clots, it creates pieces called D-dimers. ARDS is predicted by an elevated D-dimer level. The study's objective was to ascertain how the severity of COVID-19 patients at Dr. H. Abdul Moeloek in 2021 related to NLR and D-dimer levels. Analytical research with a retrospective design is being conducted. The Rank Spearman correlation test and Pearson Chi-Square analyzed medical record data for COVID-19 patients. The study was carried out in Dr. H. Abdul Moeloek in June 2022. 205 COVID-19 patients who underwent NLR and D-dimer testing and were categorized based on the severity of the condition served as the study's subjects. The test findings revealed a substantial connection between NLR and D-dimer (r=0.583), demonstrating a strong and favorable link. NLR and illness severity showed a significant relationship (r=0.49). D-dimer and illness severity also showed a strong connection (r=0.51).https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/3775illness severityimmune systemnlr.
spellingShingle Citra Suhesty
Wimba Widagdho Dinutanayo
Maria Tuntun
Hidayat Hidayat
Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity
Jurnal Kesehatan
illness severity
immune system
nlr.
title Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity
title_full Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity
title_fullStr Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity
title_full_unstemmed Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity
title_short Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity
title_sort correlation between neutrophile to lymphocyte ratio and d dimer with covid 19 severity
topic illness severity
immune system
nlr.
url https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/3775
work_keys_str_mv AT citrasuhesty correlationbetweenneutrophiletolymphocyteratioandddimerwithcovid19severity
AT wimbawidagdhodinutanayo correlationbetweenneutrophiletolymphocyteratioandddimerwithcovid19severity
AT mariatuntun correlationbetweenneutrophiletolymphocyteratioandddimerwithcovid19severity
AT hidayathidayat correlationbetweenneutrophiletolymphocyteratioandddimerwithcovid19severity