Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity
SARS-CoV-2, a lung-damaging virus, is what causes COVID-19. While a decline in lymphocyte counts suggests immune system harm, a rise in neutrophil counts reflects the severity of the inflammatory response. A high NLR value results from an increase in neutrophils and a decrease in lymphocytes. On the...
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Politeknik Kesehatan Tanjung Karang
2023-09-01
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Online Access: | https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/3775 |
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author | Citra Suhesty Wimba Widagdho Dinutanayo Maria Tuntun Hidayat Hidayat |
author_facet | Citra Suhesty Wimba Widagdho Dinutanayo Maria Tuntun Hidayat Hidayat |
author_sort | Citra Suhesty |
collection | DOAJ |
description | SARS-CoV-2, a lung-damaging virus, is what causes COVID-19. While a decline in lymphocyte counts suggests immune system harm, a rise in neutrophil counts reflects the severity of the inflammatory response. A high NLR value results from an increase in neutrophils and a decrease in lymphocytes. On the other hand, when plasmin breaks down fibrin to dissolve blood clots, it creates pieces called D-dimers. ARDS is predicted by an elevated D-dimer level. The study's objective was to ascertain how the severity of COVID-19 patients at Dr. H. Abdul Moeloek in 2021 related to NLR and D-dimer levels. Analytical research with a retrospective design is being conducted. The Rank Spearman correlation test and Pearson Chi-Square analyzed medical record data for COVID-19 patients. The study was carried out in Dr. H. Abdul Moeloek in June 2022. 205 COVID-19 patients who underwent NLR and D-dimer testing and were categorized based on the severity of the condition served as the study's subjects. The test findings revealed a substantial connection between NLR and D-dimer (r=0.583), demonstrating a strong and favorable link. NLR and illness severity showed a significant relationship (r=0.49). D-dimer and illness severity also showed a strong connection (r=0.51). |
format | Article |
id | doaj-art-0dc4bc3484c14466b00631ce38c93502 |
institution | Kabale University |
issn | 2086-7751 2548-5695 |
language | Indonesian |
publishDate | 2023-09-01 |
publisher | Politeknik Kesehatan Tanjung Karang |
record_format | Article |
series | Jurnal Kesehatan |
spelling | doaj-art-0dc4bc3484c14466b00631ce38c935022025-01-22T14:04:07ZindPoliteknik Kesehatan Tanjung KarangJurnal Kesehatan2086-77512548-56952023-09-0114238238710.26630/jk.v14i2.37753169Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 SeverityCitra Suhesty0Wimba Widagdho Dinutanayo1Maria Tuntun2Hidayat Hidayat3Poltekkes TanjungkarangPoltekkes TanjungkarangPoltekkes TanjungkarangRSUD Dr. H. Abdul MoeloekSARS-CoV-2, a lung-damaging virus, is what causes COVID-19. While a decline in lymphocyte counts suggests immune system harm, a rise in neutrophil counts reflects the severity of the inflammatory response. A high NLR value results from an increase in neutrophils and a decrease in lymphocytes. On the other hand, when plasmin breaks down fibrin to dissolve blood clots, it creates pieces called D-dimers. ARDS is predicted by an elevated D-dimer level. The study's objective was to ascertain how the severity of COVID-19 patients at Dr. H. Abdul Moeloek in 2021 related to NLR and D-dimer levels. Analytical research with a retrospective design is being conducted. The Rank Spearman correlation test and Pearson Chi-Square analyzed medical record data for COVID-19 patients. The study was carried out in Dr. H. Abdul Moeloek in June 2022. 205 COVID-19 patients who underwent NLR and D-dimer testing and were categorized based on the severity of the condition served as the study's subjects. The test findings revealed a substantial connection between NLR and D-dimer (r=0.583), demonstrating a strong and favorable link. NLR and illness severity showed a significant relationship (r=0.49). D-dimer and illness severity also showed a strong connection (r=0.51).https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/3775illness severityimmune systemnlr. |
spellingShingle | Citra Suhesty Wimba Widagdho Dinutanayo Maria Tuntun Hidayat Hidayat Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity Jurnal Kesehatan illness severity immune system nlr. |
title | Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity |
title_full | Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity |
title_fullStr | Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity |
title_full_unstemmed | Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity |
title_short | Correlation between Neutrophile to Lymphocyte Ratio and D-dimer with COVID-19 Severity |
title_sort | correlation between neutrophile to lymphocyte ratio and d dimer with covid 19 severity |
topic | illness severity immune system nlr. |
url | https://ejurnal.poltekkes-tjk.ac.id/index.php/JK/article/view/3775 |
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