Association between NT‐proBNP changes and clinical outcomes in paediatric patients with heart failure: Insights from PANORAMA‐HF and PARADIGM‐HF

Association between NT‐proBNP changes and clinical outcomes in paediatric patients with heart failure: Insights from PANORAMA‐HF and PARADIGM‐HF

Abstract Aims The PANORAMA‐HF trial demonstrated significant N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) reductions in paediatric patients with left ventricular systolic dysfunction with sacubitril/valsartan or enalapril treatment over 52 weeks. This post hoc analysis aims to correlate cha...

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Main Authors: Robert Shaddy, Jianjian Gong, Tania Garito, Susan Solar‐Yohay, Sijia Zhang, Margaret F. Prescott, Damien Bonnet, Paul F. Kantor, Michael Burch, Chad Mao, Antoinette Cilliers, Charles Canter, Yuk Law, Giorgia Grutter, Jou Kou Wang, Aamir Jeewa, Joseph Rossano, PANORAMA‐HF investigators
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:ESC Heart Failure
Subjects:
Left ventricular systolic dysfunction
NT‐proBNP
Paediatric heart failure
Sacubitril/valsartan
Online Access:https://doi.org/10.1002/ehf2.15326
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