HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy

Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium ca...

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Main Authors: Zeynep Ozcan Dag, Yuksel Işik, Yavuz Simsek, Ozlem Banu Tulmac, Demet Demiray
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2014/582890
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author Zeynep Ozcan Dag
Yuksel Işik
Yavuz Simsek
Ozlem Banu Tulmac
Demet Demiray
author_facet Zeynep Ozcan Dag
Yuksel Işik
Yavuz Simsek
Ozlem Banu Tulmac
Demet Demiray
author_sort Zeynep Ozcan Dag
collection DOAJ
description Preeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium carry an increased risk of venous thromboembolism including cerebral venous sinus thrombosis (CVST). Factor 5 leiden (FVL) is a procoagulant mutation associated primarily with venous thrombosis and pregnancy complications. We report a patient with FVL mutation who presented with CVST at 24th week of pregnancy and was diagnosed as HELLP syndrome at 34th week of pregnancy.
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institution Kabale University
issn 2090-6684
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language English
publishDate 2014-01-01
publisher Wiley
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-0d8b3b33a4f34aaa9c5fbd0804b4f0512025-02-03T01:31:04ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922014-01-01201410.1155/2014/582890582890HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during PregnancyZeynep Ozcan Dag0Yuksel Işik1Yavuz Simsek2Ozlem Banu Tulmac3Demet Demiray4Department of Gynecology and Obstetrics, Faculty of Medicine, Kirikkale University, Kirikkale, TurkeyDepartment of Gynecology and Obstetrics, Faculty of Medicine, Kirikkale University, Kirikkale, TurkeyDepartment of Gynecology and Obstetrics, Faculty of Medicine, Kirikkale University, Kirikkale, TurkeyDepartment of Gynecology and Obstetrics, Faculty of Medicine, Kirikkale University, Kirikkale, TurkeyDepartment of Gynecology and Obstetrics, Faculty of Medicine, Kirikkale University, Kirikkale, TurkeyPreeclampsia is a leading cause of maternal mortality and morbidity worldwide. The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality for women and their infants alike. Hormonal changes during pregnancy and the puerperium carry an increased risk of venous thromboembolism including cerebral venous sinus thrombosis (CVST). Factor 5 leiden (FVL) is a procoagulant mutation associated primarily with venous thrombosis and pregnancy complications. We report a patient with FVL mutation who presented with CVST at 24th week of pregnancy and was diagnosed as HELLP syndrome at 34th week of pregnancy.http://dx.doi.org/10.1155/2014/582890
spellingShingle Zeynep Ozcan Dag
Yuksel Işik
Yavuz Simsek
Ozlem Banu Tulmac
Demet Demiray
HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
Case Reports in Obstetrics and Gynecology
title HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_full HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_fullStr HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_full_unstemmed HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_short HELLP Syndrome and Cerebral Venous Sinus Thrombosis Associated with Factor V Leiden Mutation during Pregnancy
title_sort hellp syndrome and cerebral venous sinus thrombosis associated with factor v leiden mutation during pregnancy
url http://dx.doi.org/10.1155/2014/582890
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AT ozlembanutulmac hellpsyndromeandcerebralvenoussinusthrombosisassociatedwithfactorvleidenmutationduringpregnancy
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