Dynamics of an age-of-infection cholera model

A new model for the dynamics of cholera is formulated that incorporates both the infection age of infectious individuals and biological age of pathogen in the environment. The basic reproduction number is defined and proved to be a sharp threshold determining whether or not cholera dies out. Final s...

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Main Authors: Fred Brauer, Zhisheng Shuai, P. van den Driessche
Format: Article
Language:English
Published: AIMS Press 2013-07-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1335
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author Fred Brauer
Zhisheng Shuai
P. van den Driessche
author_facet Fred Brauer
Zhisheng Shuai
P. van den Driessche
author_sort Fred Brauer
collection DOAJ
description A new model for the dynamics of cholera is formulated that incorporates both the infection age of infectious individuals and biological age of pathogen in the environment. The basic reproduction number is defined and proved to be a sharp threshold determining whether or not cholera dies out. Final size relations for cholera outbreaks are derived for simplified models when input and death are neglected.
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institution Kabale University
issn 1551-0018
language English
publishDate 2013-07-01
publisher AIMS Press
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series Mathematical Biosciences and Engineering
spelling doaj-art-0d79e40d6a834f78b8870eed2366d15d2025-01-24T02:26:34ZengAIMS PressMathematical Biosciences and Engineering1551-00182013-07-01105&61335134910.3934/mbe.2013.10.1335Dynamics of an age-of-infection cholera modelFred Brauer0Zhisheng Shuai1P. van den Driessche2Department of Mathematics, University of British Columbia, Vancouver, BC V6T 1Z2Department of Mathematics and Statistics, University of Victoria, Victoria, B.C., V8W 3R4Department of Mathematics and Statistics, University of Victoria, Victoria B.C., Canada V8W 3P4A new model for the dynamics of cholera is formulated that incorporates both the infection age of infectious individuals and biological age of pathogen in the environment. The basic reproduction number is defined and proved to be a sharp threshold determining whether or not cholera dies out. Final size relations for cholera outbreaks are derived for simplified models when input and death are neglected.https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1335lyapunov functionalcholera modelfinal size.global stabilityage-of-infection
spellingShingle Fred Brauer
Zhisheng Shuai
P. van den Driessche
Dynamics of an age-of-infection cholera model
Mathematical Biosciences and Engineering
lyapunov functional
cholera model
final size.
global stability
age-of-infection
title Dynamics of an age-of-infection cholera model
title_full Dynamics of an age-of-infection cholera model
title_fullStr Dynamics of an age-of-infection cholera model
title_full_unstemmed Dynamics of an age-of-infection cholera model
title_short Dynamics of an age-of-infection cholera model
title_sort dynamics of an age of infection cholera model
topic lyapunov functional
cholera model
final size.
global stability
age-of-infection
url https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1335
work_keys_str_mv AT fredbrauer dynamicsofanageofinfectioncholeramodel
AT zhishengshuai dynamicsofanageofinfectioncholeramodel
AT pvandendriessche dynamicsofanageofinfectioncholeramodel