Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review
Viral infection is known to induce transient autoimmunity in humans. Acute cytomegalovirus (CMV) infection is implicated in occasional thrombosis formation. We here, for the first time, report a 19-year-old female who had an acute CMV infection, leading to a deep venous thrombosis and a pulmonary em...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2014/271548 |
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| author | Tsuyoshi Nakayama Mitsuteru Akahoshi Kensuke Irino Yasutaka Kimoto Yojiro Arinobu Hiroaki Niiro Hiroshi Tsukamoto Takahiko Horiuchi Koichi Akashi |
| author_facet | Tsuyoshi Nakayama Mitsuteru Akahoshi Kensuke Irino Yasutaka Kimoto Yojiro Arinobu Hiroaki Niiro Hiroshi Tsukamoto Takahiko Horiuchi Koichi Akashi |
| author_sort | Tsuyoshi Nakayama |
| collection | DOAJ |
| description | Viral infection is known to induce transient autoimmunity in humans. Acute cytomegalovirus (CMV) infection is implicated in occasional thrombosis formation. We here, for the first time, report a 19-year-old female who had an acute CMV infection, leading to a deep venous thrombosis and a pulmonary embolism along with transient appearance of lupus anticoagulant. The pathological role of antiphospholipid antibodies in CMV-mediated thrombosis is discussed. |
| format | Article |
| id | doaj-art-0d735c6c1a5c46e9a2171932ca192ae8 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-0d735c6c1a5c46e9a2171932ca192ae82025-02-03T05:53:36ZengWileyCase Reports in Rheumatology2090-68892090-68972014-01-01201410.1155/2014/271548271548Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature ReviewTsuyoshi Nakayama0Mitsuteru Akahoshi1Kensuke Irino2Yasutaka Kimoto3Yojiro Arinobu4Hiroaki Niiro5Hiroshi Tsukamoto6Takahiko Horiuchi7Koichi Akashi8Department of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanDepartment of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanDepartment of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanDepartment of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanDepartment of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanClinical Education Center, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanDepartment of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanDepartment of Internal Medicine, Kyushu University Beppu Hospital, 4546 Tsurumibaru, Beppu, Oita 874-0838, JapanDepartment of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanViral infection is known to induce transient autoimmunity in humans. Acute cytomegalovirus (CMV) infection is implicated in occasional thrombosis formation. We here, for the first time, report a 19-year-old female who had an acute CMV infection, leading to a deep venous thrombosis and a pulmonary embolism along with transient appearance of lupus anticoagulant. The pathological role of antiphospholipid antibodies in CMV-mediated thrombosis is discussed.http://dx.doi.org/10.1155/2014/271548 |
| spellingShingle | Tsuyoshi Nakayama Mitsuteru Akahoshi Kensuke Irino Yasutaka Kimoto Yojiro Arinobu Hiroaki Niiro Hiroshi Tsukamoto Takahiko Horiuchi Koichi Akashi Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review Case Reports in Rheumatology |
| title | Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review |
| title_full | Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review |
| title_fullStr | Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review |
| title_full_unstemmed | Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review |
| title_short | Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review |
| title_sort | transient antiphospholipid syndrome associated with primary cytomegalovirus infection a case report and literature review |
| url | http://dx.doi.org/10.1155/2014/271548 |
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