Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review
Background The oral microbiota is a diverse and complex community that maintains a delicate balance. When this balance is disturbed, it can lead to acute and chronic infectious diseases such as dental caries and periodontitis, significantly affecting people’s quality of life. Developing a new antimi...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2025.2457518 |
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| author | Jiajun Xin Hao Zhang Yushen Li Yifei Dai Xiantao Chen Jiatong Zou Rui Wang Zhihui Liu Bowei Wang |
| author_facet | Jiajun Xin Hao Zhang Yushen Li Yifei Dai Xiantao Chen Jiatong Zou Rui Wang Zhihui Liu Bowei Wang |
| author_sort | Jiajun Xin |
| collection | DOAJ |
| description | Background The oral microbiota is a diverse and complex community that maintains a delicate balance. When this balance is disturbed, it can lead to acute and chronic infectious diseases such as dental caries and periodontitis, significantly affecting people’s quality of life. Developing a new antimicrobial strategy to deal with the increasing microbial variability and resistance is important. Cold atmospheric plasma (CAP), as the fourth state of matter, has gradually become a hot topic in the field of biomedicine due to its good antibacterial, anti-inflammatory, and anti-tumor capabilities. It is expected to become a major asset in the regulation of oral microbiota.Methods We conducted a search in PubMed, Medline, and Wiley databases, focusing on studies related to CAP and oral pathogenic microorganisms. We explored the biological effects of CAP and summarized the antimicrobial mechanisms behind it.Results Numerous articles have shown that CAP has a potent antimicrobial effect against common oral pathogens, including bacteria, fungi, and viruses, primarily due to the synergy of various factors, especially reactive oxygen and nitrogen species.Conclusions CAP is effective against various oral pathogenic microorganisms, and it is anticipated to offer a new approach to treating oral infectious diseases. The future objective is to precisely adjust the parameters of CAP to ensure safety and efficacy, and subsequently develop a comprehensive CAP treatment protocol. Achieving this objective is crucial for the clinical application of CAP, and further research is necessary. |
| format | Article |
| id | doaj-art-0d683712fe934c5d886fbe69177566aa |
| institution | Kabale University |
| issn | 0785-3890 1365-2060 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj-art-0d683712fe934c5d886fbe69177566aa2025-01-27T08:10:18ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2025.2457518Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative reviewJiajun Xin0Hao Zhang1Yushen Li2Yifei Dai3Xiantao Chen4Jiatong Zou5Rui Wang6Zhihui Liu7Bowei Wang8Department of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People’s Republic of ChinaDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, People’s Republic of ChinaBackground The oral microbiota is a diverse and complex community that maintains a delicate balance. When this balance is disturbed, it can lead to acute and chronic infectious diseases such as dental caries and periodontitis, significantly affecting people’s quality of life. Developing a new antimicrobial strategy to deal with the increasing microbial variability and resistance is important. Cold atmospheric plasma (CAP), as the fourth state of matter, has gradually become a hot topic in the field of biomedicine due to its good antibacterial, anti-inflammatory, and anti-tumor capabilities. It is expected to become a major asset in the regulation of oral microbiota.Methods We conducted a search in PubMed, Medline, and Wiley databases, focusing on studies related to CAP and oral pathogenic microorganisms. We explored the biological effects of CAP and summarized the antimicrobial mechanisms behind it.Results Numerous articles have shown that CAP has a potent antimicrobial effect against common oral pathogens, including bacteria, fungi, and viruses, primarily due to the synergy of various factors, especially reactive oxygen and nitrogen species.Conclusions CAP is effective against various oral pathogenic microorganisms, and it is anticipated to offer a new approach to treating oral infectious diseases. The future objective is to precisely adjust the parameters of CAP to ensure safety and efficacy, and subsequently develop a comprehensive CAP treatment protocol. Achieving this objective is crucial for the clinical application of CAP, and further research is necessary.https://www.tandfonline.com/doi/10.1080/07853890.2025.2457518Cold atmospheric plasmaoral microorganismsoral infectious diseaseantimicrobialreactive oxygen and nitrogen species |
| spellingShingle | Jiajun Xin Hao Zhang Yushen Li Yifei Dai Xiantao Chen Jiatong Zou Rui Wang Zhihui Liu Bowei Wang Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review Annals of Medicine Cold atmospheric plasma oral microorganisms oral infectious disease antimicrobial reactive oxygen and nitrogen species |
| title | Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review |
| title_full | Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review |
| title_fullStr | Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review |
| title_full_unstemmed | Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review |
| title_short | Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review |
| title_sort | effect of cold atmospheric plasma on common oral pathogenic microorganisms a narrative review |
| topic | Cold atmospheric plasma oral microorganisms oral infectious disease antimicrobial reactive oxygen and nitrogen species |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2025.2457518 |
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