The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome
The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS. The non-MS group (n=105) was comprised of healthy individuals with normal...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/767968 |
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| author | Chi-Hua Yen Nae-Cherng Yang Bor-Jen Lee Jui-Yuan Lin Simon Hsia Ping-Ting Lin |
| author_facet | Chi-Hua Yen Nae-Cherng Yang Bor-Jen Lee Jui-Yuan Lin Simon Hsia Ping-Ting Lin |
| author_sort | Chi-Hua Yen |
| collection | DOAJ |
| description | The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS. The non-MS group (n=105) was comprised of healthy individuals with normal blood biochemical values. The plasma coenzyme Q10, vitamin E concentrations, lipid profiles, and antioxidant enzymes levels (catalase, superoxide dismutase, and glutathione peroxidase) were measured. The subjects with MS had significantly higher concentrations of plasma coenzyme Q10 and vitamin E than those in the non-MS group, but these differences were not significant after being normalized for triglyceride level. The levels of antioxidant enzymes were significantly lower in the MS group than in the non-MS group. The subjects with the higher antioxidant enzymes activities had significant reductions in the risk of MS (P<0.01) after being adjusted for coenzyme Q10 and vitamin E. In conclusion, the subjects with MS might be under higher oxidative stress resulting in low levels of antioxidant enzyme activities. A higher level of antioxidant enzymes activities was significantly associated with a reduction in the risk of MS independent of the levels of coenzyme Q10 and vitamin E. |
| format | Article |
| id | doaj-art-0d52accacd064ecfbeb604a18280ae2f |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-0d52accacd064ecfbeb604a18280ae2f2025-02-03T01:10:06ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/767968767968The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic SyndromeChi-Hua Yen0Nae-Cherng Yang1Bor-Jen Lee2Jui-Yuan Lin3Simon Hsia4Ping-Ting Lin5Department of Family and Community Medicine, Chung Shan Medical University Hospital, Taichung 40201, TaiwanSchool of Nutrition, Chung Shan Medical University, Taichung 40201, TaiwanThe Intensive Care Unit, Taichung Veterans General Hospital, Taichung 40705, TaiwanSchool of Nutrition, Chung Shan Medical University, Taichung 40201, TaiwanDepartment of Nutrition and Institute of Biomedical Nutrition, Hungkuang University, Taichung 43346, TaiwanSchool of Nutrition, Chung Shan Medical University, Taichung 40201, TaiwanThe purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS. The non-MS group (n=105) was comprised of healthy individuals with normal blood biochemical values. The plasma coenzyme Q10, vitamin E concentrations, lipid profiles, and antioxidant enzymes levels (catalase, superoxide dismutase, and glutathione peroxidase) were measured. The subjects with MS had significantly higher concentrations of plasma coenzyme Q10 and vitamin E than those in the non-MS group, but these differences were not significant after being normalized for triglyceride level. The levels of antioxidant enzymes were significantly lower in the MS group than in the non-MS group. The subjects with the higher antioxidant enzymes activities had significant reductions in the risk of MS (P<0.01) after being adjusted for coenzyme Q10 and vitamin E. In conclusion, the subjects with MS might be under higher oxidative stress resulting in low levels of antioxidant enzyme activities. A higher level of antioxidant enzymes activities was significantly associated with a reduction in the risk of MS independent of the levels of coenzyme Q10 and vitamin E.http://dx.doi.org/10.1155/2013/767968 |
| spellingShingle | Chi-Hua Yen Nae-Cherng Yang Bor-Jen Lee Jui-Yuan Lin Simon Hsia Ping-Ting Lin The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome The Scientific World Journal |
| title | The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome |
| title_full | The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome |
| title_fullStr | The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome |
| title_full_unstemmed | The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome |
| title_short | The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome |
| title_sort | antioxidant status and concentrations of coenzyme q10 and vitamin e in metabolic syndrome |
| url | http://dx.doi.org/10.1155/2013/767968 |
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