Considerations of growth factor and material use in bone tissue engineering using biodegradable scaffolds in vitro and in vivo

Considerations of growth factor and material use in bone tissue engineering using biodegradable scaffolds in vitro and in vivo

Abstract Bone tissue engineering aims to harness materials to develop functional bone tissue to heal ‘critical-sized’ bone defects. This study examined a robust, coated poly(caprolactone) trimethacrylate (PCL-TMA) 3D-printable scaffold designed to augment bone formation. Following optimisation of th...

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Bibliographic Details
Main Authors: Karen M. Marshall, Jonathan P. Wojciechowski, Vineetha Jayawarna, Abshar Hasan, Cécile Echalier, Øystein Øvrebø, Tao Yang, Kun Zhou, Janos M. Kanczler, Alvaro Mata, Manuel Salmeron-Sanchez, Molly M. Stevens, Richard O. C. Oreffo
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Bioactive coating
Biomaterial
Bone tissue engineering
CAM assay
Animal models
Online Access:https://doi.org/10.1038/s41598-024-75198-3
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