Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review

This study was conducted to summarize the results of studies investigating the role of neutrophil to lymphocyte ratio (NLR) in epilepsy. The search was conducted on PubMed, Scopus, and Web of Science up to December 25, 2021. Finally, a total of seven studies were included in the review. The NLR in p...

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Main Authors: Samaneh Hosseini, Amir Mohammad Eghbalnejad Mofrad, Peyman Mokarian, Shima Nourigheimasi, Amir Azarhomayoun, Shokoufeh Khanzadeh, Saba Habibzadeh, Arshin Ghaedi
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2022/4973996
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author Samaneh Hosseini
Amir Mohammad Eghbalnejad Mofrad
Peyman Mokarian
Shima Nourigheimasi
Amir Azarhomayoun
Shokoufeh Khanzadeh
Saba Habibzadeh
Arshin Ghaedi
author_facet Samaneh Hosseini
Amir Mohammad Eghbalnejad Mofrad
Peyman Mokarian
Shima Nourigheimasi
Amir Azarhomayoun
Shokoufeh Khanzadeh
Saba Habibzadeh
Arshin Ghaedi
author_sort Samaneh Hosseini
collection DOAJ
description This study was conducted to summarize the results of studies investigating the role of neutrophil to lymphocyte ratio (NLR) in epilepsy. The search was conducted on PubMed, Scopus, and Web of Science up to December 25, 2021. Finally, a total of seven studies were included in the review. The NLR in patients who were in the acute phase was higher than that of healthy. NLR in the patients who were in either acute or subacute phase was higher than in healthy controls. A significant difference in NLR levels between the acute and subacute phases was also noted. Epilepsy is one of the most important neurological diseases in the world, and millions of people around the world suffer from it, and a cheap and fast biomarker is needed for it. The interesting thing is that inflammation plays a role in epilepsy, and elevated NLR value can be a good biomarker of inflammation and, as a result, for epilepsy.
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series Mediators of Inflammation
spelling doaj-art-0d2714ce4001449ea6f01b3793a80fa52025-02-03T01:24:09ZengWileyMediators of Inflammation1466-18612022-01-01202210.1155/2022/4973996Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic ReviewSamaneh Hosseini0Amir Mohammad Eghbalnejad Mofrad1Peyman Mokarian2Shima Nourigheimasi3Amir Azarhomayoun4Shokoufeh Khanzadeh5Saba Habibzadeh6Arshin Ghaedi7Neurosciences Research CenterAhvaz Jundishapur University of Medical SciencesFasa University of Medical SciencesSchool of MedicineSina Trauma and Surgery Research CenterStudent Research CommitteeClinical Research Development Unit of Children Hospital Tabriz University of Medical ScienceStudent Research CommitteeThis study was conducted to summarize the results of studies investigating the role of neutrophil to lymphocyte ratio (NLR) in epilepsy. The search was conducted on PubMed, Scopus, and Web of Science up to December 25, 2021. Finally, a total of seven studies were included in the review. The NLR in patients who were in the acute phase was higher than that of healthy. NLR in the patients who were in either acute or subacute phase was higher than in healthy controls. A significant difference in NLR levels between the acute and subacute phases was also noted. Epilepsy is one of the most important neurological diseases in the world, and millions of people around the world suffer from it, and a cheap and fast biomarker is needed for it. The interesting thing is that inflammation plays a role in epilepsy, and elevated NLR value can be a good biomarker of inflammation and, as a result, for epilepsy.http://dx.doi.org/10.1155/2022/4973996
spellingShingle Samaneh Hosseini
Amir Mohammad Eghbalnejad Mofrad
Peyman Mokarian
Shima Nourigheimasi
Amir Azarhomayoun
Shokoufeh Khanzadeh
Saba Habibzadeh
Arshin Ghaedi
Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review
Mediators of Inflammation
title Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review
title_full Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review
title_fullStr Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review
title_full_unstemmed Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review
title_short Neutrophil to Lymphocyte Ratio in Epilepsy: A Systematic Review
title_sort neutrophil to lymphocyte ratio in epilepsy a systematic review
url http://dx.doi.org/10.1155/2022/4973996
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