WDR36 Regulates Trophectoderm Differentiation During Human Preimplantation Embryonic Development Through Glycolytic Metabolism

WDR36 Regulates Trophectoderm Differentiation During Human Preimplantation Embryonic Development Through Glycolytic Metabolism

Abstract Mammalian pre‐implantation development is a complex process involving sophisticated regulatory dynamics. WD repeat domain 36 (WDR36) is known to play a critical role in mouse early embryonic development, but its regulatory function in human embryogenesis is still elusive due to limited acce...

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Main Authors: Shiyu An, Shuyue Hou, Feifei Xu, Huanyu Yan, Wenyi Zhang, Jinfeng Xiang, Haoran Chen, Hanwen Zhang, Lingling Dong, Xiaobin Sun, Ran Huo, Yun Chen, Xi Wang, Yang Yang
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
glycolysis
human embryonic development
LDHA
trophectoderm lineage commitment
WDR36
Online Access:https://doi.org/10.1002/advs.202412222
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