INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera

The inhibitory effect of Bluméa balsamifera extract on the nucleation, growth, and aggregation phases of calcium oxalate formation has been studied. Plant samples were extracted by the maceration method with 80.00% ethanol. The results showed that the moisture content of Bluméa balsamifera extract w...

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Main Authors: Nguyen Pham Tuan, Bang Hong Lam, Nguyen Pham Tu, Le Thao Nguyen, Tran Duc Tai
Format: Article
Language:English
Published: Dalat University 2021-02-01
Series:Tạp chí Khoa học Đại học Đà Lạt
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Online Access:http://tckh.dlu.edu.vn/index.php/tckhdhdl/article/view/691
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author Nguyen Pham Tuan
Bang Hong Lam
Nguyen Pham Tu
Le Thao Nguyen
Tran Duc Tai
author_facet Nguyen Pham Tuan
Bang Hong Lam
Nguyen Pham Tu
Le Thao Nguyen
Tran Duc Tai
author_sort Nguyen Pham Tuan
collection DOAJ
description The inhibitory effect of Bluméa balsamifera extract on the nucleation, growth, and aggregation phases of calcium oxalate formation has been studied. Plant samples were extracted by the maceration method with 80.00% ethanol. The results showed that the moisture content of Bluméa balsamifera extract was 82.83% and the yield was 5.79%. Bluméa balsamifera extract contains bioactive compounds including alkaloids, flavonoids, saponins, terpenoids, tannins, and phenol. Bluméa balsamifera extract has the ability to inhibit the nucleation of calcium oxalate with an IC50 value of 4.25 mg/ml. Bluméa balsamifera extract has a significant inhibitory effect on the growth of calcium oxalate crystals with an IC50 value of 2.99 mg/ml. Finally, Bluméa balsamifera extract is capable of inhibiting the aggregation of calcium oxalate with an IC50 value of 2.56 mg/ml.
format Article
id doaj-art-0ce199865d504adfbdbfb4744443d25e
institution Kabale University
issn 0866-787X
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language English
publishDate 2021-02-01
publisher Dalat University
record_format Article
series Tạp chí Khoa học Đại học Đà Lạt
spelling doaj-art-0ce199865d504adfbdbfb4744443d25e2025-02-02T22:05:01ZengDalat UniversityTạp chí Khoa học Đại học Đà Lạt0866-787X0866-787X2021-02-0111131310.37569/DalatUniversity.11.1.691(2021)346INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamiferaNguyen Pham Tuan0Bang Hong Lam1Nguyen Pham Tu2Le Thao Nguyen3Tran Duc Tai4Trung tâm Công nghệ Sinh học tỉnh An GiangTrường Đại học An GiangTrung tâm Công nghệ Sinh học tỉnh An GiangĐại học GachonĐại học GachonThe inhibitory effect of Bluméa balsamifera extract on the nucleation, growth, and aggregation phases of calcium oxalate formation has been studied. Plant samples were extracted by the maceration method with 80.00% ethanol. The results showed that the moisture content of Bluméa balsamifera extract was 82.83% and the yield was 5.79%. Bluméa balsamifera extract contains bioactive compounds including alkaloids, flavonoids, saponins, terpenoids, tannins, and phenol. Bluméa balsamifera extract has the ability to inhibit the nucleation of calcium oxalate with an IC50 value of 4.25 mg/ml. Bluméa balsamifera extract has a significant inhibitory effect on the growth of calcium oxalate crystals with an IC50 value of 2.99 mg/ml. Finally, Bluméa balsamifera extract is capable of inhibiting the aggregation of calcium oxalate with an IC50 value of 2.56 mg/ml.http://tckh.dlu.edu.vn/index.php/tckhdhdl/article/view/691calcium oxalatecây từ bingưng tụphát triểnsỏi thận.
spellingShingle Nguyen Pham Tuan
Bang Hong Lam
Nguyen Pham Tu
Le Thao Nguyen
Tran Duc Tai
INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera
Tạp chí Khoa học Đại học Đà Lạt
calcium oxalate
cây từ bi
ngưng tụ
phát triển
sỏi thận.
title INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera
title_full INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera
title_fullStr INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera
title_full_unstemmed INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera
title_short INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera
title_sort inhibition of calcium oxalate crystallization causing kidney stones in vitro by an extract of blumea balsamifera
topic calcium oxalate
cây từ bi
ngưng tụ
phát triển
sỏi thận.
url http://tckh.dlu.edu.vn/index.php/tckhdhdl/article/view/691
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AT banghonglam inhibitionofcalciumoxalatecrystallizationcausingkidneystonesinvitrobyanextractofblumeabalsamifera
AT nguyenphamtu inhibitionofcalciumoxalatecrystallizationcausingkidneystonesinvitrobyanextractofblumeabalsamifera
AT lethaonguyen inhibitionofcalciumoxalatecrystallizationcausingkidneystonesinvitrobyanextractofblumeabalsamifera
AT tranductai inhibitionofcalciumoxalatecrystallizationcausingkidneystonesinvitrobyanextractofblumeabalsamifera