INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera
The inhibitory effect of Bluméa balsamifera extract on the nucleation, growth, and aggregation phases of calcium oxalate formation has been studied. Plant samples were extracted by the maceration method with 80.00% ethanol. The results showed that the moisture content of Bluméa balsamifera extract w...
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Dalat University
2021-02-01
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Series: | Tạp chí Khoa học Đại học Đà Lạt |
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Online Access: | http://tckh.dlu.edu.vn/index.php/tckhdhdl/article/view/691 |
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author | Nguyen Pham Tuan Bang Hong Lam Nguyen Pham Tu Le Thao Nguyen Tran Duc Tai |
author_facet | Nguyen Pham Tuan Bang Hong Lam Nguyen Pham Tu Le Thao Nguyen Tran Duc Tai |
author_sort | Nguyen Pham Tuan |
collection | DOAJ |
description | The inhibitory effect of Bluméa balsamifera extract on the nucleation, growth, and aggregation phases of calcium oxalate formation has been studied. Plant samples were extracted by the maceration method with 80.00% ethanol. The results showed that the moisture content of Bluméa balsamifera extract was 82.83% and the yield was 5.79%. Bluméa balsamifera extract contains bioactive compounds including alkaloids, flavonoids, saponins, terpenoids, tannins, and phenol. Bluméa balsamifera extract has the ability to inhibit the nucleation of calcium oxalate with an IC50 value of 4.25 mg/ml. Bluméa balsamifera extract has a significant inhibitory effect on the growth of calcium oxalate crystals with an IC50 value of 2.99 mg/ml. Finally, Bluméa balsamifera extract is capable of inhibiting the aggregation of calcium oxalate with an IC50 value of 2.56 mg/ml. |
format | Article |
id | doaj-art-0ce199865d504adfbdbfb4744443d25e |
institution | Kabale University |
issn | 0866-787X 0866-787X |
language | English |
publishDate | 2021-02-01 |
publisher | Dalat University |
record_format | Article |
series | Tạp chí Khoa học Đại học Đà Lạt |
spelling | doaj-art-0ce199865d504adfbdbfb4744443d25e2025-02-02T22:05:01ZengDalat UniversityTạp chí Khoa học Đại học Đà Lạt0866-787X0866-787X2021-02-0111131310.37569/DalatUniversity.11.1.691(2021)346INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamiferaNguyen Pham Tuan0Bang Hong Lam1Nguyen Pham Tu2Le Thao Nguyen3Tran Duc Tai4Trung tâm Công nghệ Sinh học tỉnh An GiangTrường Đại học An GiangTrung tâm Công nghệ Sinh học tỉnh An GiangĐại học GachonĐại học GachonThe inhibitory effect of Bluméa balsamifera extract on the nucleation, growth, and aggregation phases of calcium oxalate formation has been studied. Plant samples were extracted by the maceration method with 80.00% ethanol. The results showed that the moisture content of Bluméa balsamifera extract was 82.83% and the yield was 5.79%. Bluméa balsamifera extract contains bioactive compounds including alkaloids, flavonoids, saponins, terpenoids, tannins, and phenol. Bluméa balsamifera extract has the ability to inhibit the nucleation of calcium oxalate with an IC50 value of 4.25 mg/ml. Bluméa balsamifera extract has a significant inhibitory effect on the growth of calcium oxalate crystals with an IC50 value of 2.99 mg/ml. Finally, Bluméa balsamifera extract is capable of inhibiting the aggregation of calcium oxalate with an IC50 value of 2.56 mg/ml.http://tckh.dlu.edu.vn/index.php/tckhdhdl/article/view/691calcium oxalatecây từ bingưng tụphát triểnsỏi thận. |
spellingShingle | Nguyen Pham Tuan Bang Hong Lam Nguyen Pham Tu Le Thao Nguyen Tran Duc Tai INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera Tạp chí Khoa học Đại học Đà Lạt calcium oxalate cây từ bi ngưng tụ phát triển sỏi thận. |
title | INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera |
title_full | INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera |
title_fullStr | INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera |
title_full_unstemmed | INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera |
title_short | INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION CAUSING KIDNEY STONES IN VITRO BY AN EXTRACT OF Bluméa balsamifera |
title_sort | inhibition of calcium oxalate crystallization causing kidney stones in vitro by an extract of blumea balsamifera |
topic | calcium oxalate cây từ bi ngưng tụ phát triển sỏi thận. |
url | http://tckh.dlu.edu.vn/index.php/tckhdhdl/article/view/691 |
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