UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form
A new simple, rapid, accurate, sensitive and precise spectrophotometric method in ultra violet region has been developed for determination of acipimox (ACX) in bulk and capsule dosage form. Acipimox exhibited maximum absorbance at 231 nm with apparent molar absorptivity of 1.5104 × 104 in distilled...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/790531 |
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| author | A. Elphine Prabahar B. Thangabalan R. Kalaichelvi P. Vijayaraj Kumar |
| author_facet | A. Elphine Prabahar B. Thangabalan R. Kalaichelvi P. Vijayaraj Kumar |
| author_sort | A. Elphine Prabahar |
| collection | DOAJ |
| description | A new simple, rapid, accurate, sensitive and precise spectrophotometric method in ultra violet region has been developed for determination of acipimox (ACX) in bulk and capsule dosage form. Acipimox exhibited maximum absorbance at 231 nm with apparent molar absorptivity of 1.5104 × 104 in distilled water. Beer’s law was found to be obeyed in the concentration range 1-10 μg mL-1. Correlation coefficient was found to be 0.9998. The developed method was validated respect to linearity, precision, accuracy. The proposed method is useful for the routine estimation of ACX in bulk and capsule dosage form. |
| format | Article |
| id | doaj-art-0cd1642ad2a649339f924f39b4ed35d1 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-0cd1642ad2a649339f924f39b4ed35d12025-02-03T05:50:54ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-01641117112010.1155/2009/790531UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage FormA. Elphine Prabahar0B. Thangabalan1R. Kalaichelvi2P. Vijayaraj Kumar3Department of Pharmacy, Donbosco PG College, Vatticherukuru Mandal, Guntur-522 017, IndiaDepartment of Pharmacy, Donbosco PG College, Vatticherukuru Mandal, Guntur-522 017, IndiaK.C. Reddy Institute of Pharmaceuatical Sciences, Jangamguntla Palem, Medikonduru Mandal, Guntur-522 348, IndiaBharat Instite of Pharmacy, Mangalpally Village, Ibrahimpatnam, PR Dist.-501506, IndiaA new simple, rapid, accurate, sensitive and precise spectrophotometric method in ultra violet region has been developed for determination of acipimox (ACX) in bulk and capsule dosage form. Acipimox exhibited maximum absorbance at 231 nm with apparent molar absorptivity of 1.5104 × 104 in distilled water. Beer’s law was found to be obeyed in the concentration range 1-10 μg mL-1. Correlation coefficient was found to be 0.9998. The developed method was validated respect to linearity, precision, accuracy. The proposed method is useful for the routine estimation of ACX in bulk and capsule dosage form.http://dx.doi.org/10.1155/2009/790531 |
| spellingShingle | A. Elphine Prabahar B. Thangabalan R. Kalaichelvi P. Vijayaraj Kumar UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form E-Journal of Chemistry |
| title | UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form |
| title_full | UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form |
| title_fullStr | UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form |
| title_full_unstemmed | UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form |
| title_short | UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form |
| title_sort | uv spectrophotometric estimation of acipimox inbulk and capsule dosage form |
| url | http://dx.doi.org/10.1155/2009/790531 |
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