Treatment of primary esophageal lymphomas: A review
Primary esophageal lymphoma is a rare malignancy that is difficult to diagnose and treat. While there have been significant advances in understanding the pathogenesis, clinical features, and treatment options, there is a lack of consensus on the most effective treatment approach. This literature rev...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1475153/full |
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| author | Joe El Khoury Remy Daou Neal Kim Josiane Bou Eid Brandon Imber Joachim Yahalom Carla Hajj |
| author_facet | Joe El Khoury Remy Daou Neal Kim Josiane Bou Eid Brandon Imber Joachim Yahalom Carla Hajj |
| author_sort | Joe El Khoury |
| collection | DOAJ |
| description | Primary esophageal lymphoma is a rare malignancy that is difficult to diagnose and treat. While there have been significant advances in understanding the pathogenesis, clinical features, and treatment options, there is a lack of consensus on the most effective treatment approach. This literature review provides a comprehensive overview of the use of available treatment options for primary esophageal lymphoma, including surgery, radiotherapy, and chemotherapy. The review also highlights the current knowledge gaps that need to be addressed through further research. While no single treatment modality has emerged as a clear front-runner, a combination of these treatments may be the most effective approach in managing primary esophageal lymphoma, tailored to the histological subtypes. |
| format | Article |
| id | doaj-art-0cc90499c5974c668855f6eb7c222293 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-0cc90499c5974c668855f6eb7c2222932025-02-06T05:21:48ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-02-011510.3389/fonc.2025.14751531475153Treatment of primary esophageal lymphomas: A reviewJoe El Khoury0Remy Daou1Neal Kim2Josiane Bou Eid3Brandon Imber4Joachim Yahalom5Carla Hajj6Department of Family Medicine, Saint Joseph University, Beirut, LebanonDepartment of Family Medicine, Saint Joseph University, Beirut, LebanonDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United StatesDepartment of Family Medicine, Saint Joseph University, Beirut, LebanonDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United StatesDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United StatesDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United StatesPrimary esophageal lymphoma is a rare malignancy that is difficult to diagnose and treat. While there have been significant advances in understanding the pathogenesis, clinical features, and treatment options, there is a lack of consensus on the most effective treatment approach. This literature review provides a comprehensive overview of the use of available treatment options for primary esophageal lymphoma, including surgery, radiotherapy, and chemotherapy. The review also highlights the current knowledge gaps that need to be addressed through further research. While no single treatment modality has emerged as a clear front-runner, a combination of these treatments may be the most effective approach in managing primary esophageal lymphoma, tailored to the histological subtypes.https://www.frontiersin.org/articles/10.3389/fonc.2025.1475153/fullesophageal lymphomaDLBCLfollicular lymphomaradiation treatmentMALT lymphoma |
| spellingShingle | Joe El Khoury Remy Daou Neal Kim Josiane Bou Eid Brandon Imber Joachim Yahalom Carla Hajj Treatment of primary esophageal lymphomas: A review Frontiers in Oncology esophageal lymphoma DLBCL follicular lymphoma radiation treatment MALT lymphoma |
| title | Treatment of primary esophageal lymphomas: A review |
| title_full | Treatment of primary esophageal lymphomas: A review |
| title_fullStr | Treatment of primary esophageal lymphomas: A review |
| title_full_unstemmed | Treatment of primary esophageal lymphomas: A review |
| title_short | Treatment of primary esophageal lymphomas: A review |
| title_sort | treatment of primary esophageal lymphomas a review |
| topic | esophageal lymphoma DLBCL follicular lymphoma radiation treatment MALT lymphoma |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1475153/full |
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