Risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease
Background/Aim: Functional dyspepsia, erosive and non-erosive gastroesophageal reflux disease (GERD) present a major health burden, adversely effecting quality of life. A range of factors are hypothesised to have a positive and negative influence on these diseases. This study aimed to explore the ri...
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| Language: | English |
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Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine
2024-01-01
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| Series: | Scripta Medica |
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| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2024/2490-33292406735M.pdf |
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| author | Malik Ayesha Din Rafi Ud Asif Mahrosh Naeem Iqra Habib Aamir Khan Asma Arshad |
| author_facet | Malik Ayesha Din Rafi Ud Asif Mahrosh Naeem Iqra Habib Aamir Khan Asma Arshad |
| author_sort | Malik Ayesha |
| collection | DOAJ |
| description | Background/Aim: Functional dyspepsia, erosive and non-erosive gastroesophageal reflux disease (GERD) present a major health burden, adversely effecting quality of life. A range of factors are hypothesised to have a positive and negative influence on these diseases. This study aimed to explore the risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease and its subgroups. Methods: A cross-sectional study was conducted at Combined Military Hospital (CMH), Lahore, Pakistan, from January to June 2024. Two hundred and twenty-two patients were included and interviewed to fill a tri-section questionnaire comprising a self-designed comprehensive health survey, food frequency questionnaire, gastroesophageal reflux disease questionnaire (GERD-Q), Rome IV criteria and hospital anxiety and depression scale (HADS). Results: Participants consisted of 70 controls, 38 GERD, 24 non-erosive reflux disease, 56 functional dyspepsia and 24 overlap reflux-dyspepsia syndrome patients. Subgroups included symptomatic and asymptomatic erosive oesophagitis, epigastric pain syndrome, postprandial distress syndrome and overlap syndrome. Older age, higher body mass index (BMI), male gender, low vegetable and yogurt intake, smoking, frequent red meat, high tea/caffeine intake, no postprandial exercise and a short dinner sleep interval were risk factors for GERD and symptomatic erosive esophagitis. Low BMI, female gender and anxiety were strongly associated with functional dyspepsia and non-erosive reflux disease. Conclusion: Age, BMI, gender, tobacco, anxiety, depression, dietary habits and food frequencies are significant risk factors of dyspepsia and reflux disease. |
| format | Article |
| id | doaj-art-0cc61b0891a94814a78bf590eec93658 |
| institution | Kabale University |
| issn | 2490-3329 2303-7954 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine |
| record_format | Article |
| series | Scripta Medica |
| spelling | doaj-art-0cc61b0891a94814a78bf590eec936582025-02-05T13:19:48ZengMedical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of MedicineScripta Medica2490-33292303-79542024-01-0155673574110.5937/scriptamed55-533272490-33292406735MRisk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux diseaseMalik Ayesha0https://orcid.org/0009-0001-4564-4200Din Rafi Ud1https://orcid.org/0009-0005-3306-3109Asif Mahrosh2https://orcid.org/0000-0001-8960-9565Naeem Iqra3https://orcid.org/0009-0008-4139-9114Habib Aamir4https://orcid.org/0009-0004-6527-9871Khan Asma Arshad5https://orcid.org/0009-0007-1429-7107Combined Military Hospital, Department of Gastroenterology, Lahore, PakistanCombined Military Hospital, Department of Gastroenterology, Lahore, PakistanCombined Military Hospital, Department of Medicine, Lahore, PakistanTehsil Headquarters, Department of Medicine, Chichawatni, PakistanCombined Military Hospital, Department of Gastroenterology, Lahore, PakistanCombined Military Hospital, Department of Gastroenterology, Lahore, PakistanBackground/Aim: Functional dyspepsia, erosive and non-erosive gastroesophageal reflux disease (GERD) present a major health burden, adversely effecting quality of life. A range of factors are hypothesised to have a positive and negative influence on these diseases. This study aimed to explore the risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease and its subgroups. Methods: A cross-sectional study was conducted at Combined Military Hospital (CMH), Lahore, Pakistan, from January to June 2024. Two hundred and twenty-two patients were included and interviewed to fill a tri-section questionnaire comprising a self-designed comprehensive health survey, food frequency questionnaire, gastroesophageal reflux disease questionnaire (GERD-Q), Rome IV criteria and hospital anxiety and depression scale (HADS). Results: Participants consisted of 70 controls, 38 GERD, 24 non-erosive reflux disease, 56 functional dyspepsia and 24 overlap reflux-dyspepsia syndrome patients. Subgroups included symptomatic and asymptomatic erosive oesophagitis, epigastric pain syndrome, postprandial distress syndrome and overlap syndrome. Older age, higher body mass index (BMI), male gender, low vegetable and yogurt intake, smoking, frequent red meat, high tea/caffeine intake, no postprandial exercise and a short dinner sleep interval were risk factors for GERD and symptomatic erosive esophagitis. Low BMI, female gender and anxiety were strongly associated with functional dyspepsia and non-erosive reflux disease. Conclusion: Age, BMI, gender, tobacco, anxiety, depression, dietary habits and food frequencies are significant risk factors of dyspepsia and reflux disease.https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2024/2490-33292406735M.pdfanxietydepressiondyspepsiagastroesophageal refluxrisk factors |
| spellingShingle | Malik Ayesha Din Rafi Ud Asif Mahrosh Naeem Iqra Habib Aamir Khan Asma Arshad Risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease Scripta Medica anxiety depression dyspepsia gastroesophageal reflux risk factors |
| title | Risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease |
| title_full | Risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease |
| title_fullStr | Risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease |
| title_full_unstemmed | Risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease |
| title_short | Risk factors of functional dyspepsia, gastrointestinal reflux disease and non-erosive reflux disease |
| title_sort | risk factors of functional dyspepsia gastrointestinal reflux disease and non erosive reflux disease |
| topic | anxiety depression dyspepsia gastroesophageal reflux risk factors |
| url | https://scindeks-clanci.ceon.rs/data/pdf/2490-3329/2024/2490-33292406735M.pdf |
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