Esophageal Involvement and Bleeding in Bullous Pemphigoid Disease
Bullous pemphigoid (BP) is the most common autoimmune bullous disorder and is characterized by autoantibodies against hemidesmosomal proteins in the skin and mucous membranes. BP typically presents as large, fluid-filled blisters on normal skin or red, enflamed areas of skin, mainly in the armpits,...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2024-11-01
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| Series: | Caucasian Medical Journal |
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| Online Access: | https://caucasianmedj.com/articles/esophageal-involvement-and-bleeding-in-bullous-pemphigoid-disease/doi/cmj.galenos.2024.96268 |
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| _version_ | 1832593906329452544 |
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| author | Kerem Kenarlı Derya Arı Musa Caner Yılmaz |
| author_facet | Kerem Kenarlı Derya Arı Musa Caner Yılmaz |
| author_sort | Kerem Kenarlı |
| collection | DOAJ |
| description | Bullous pemphigoid (BP) is the most common autoimmune bullous disorder and is characterized by autoantibodies against hemidesmosomal proteins in the skin and mucous membranes. BP typically presents as large, fluid-filled blisters on normal skin or red, enflamed areas of skin, mainly in the armpits, lower abdomen, inner thighs, and groin. Blisters on the lining of the oral and pharyngeal mucosa occur in up to 35% of cases, but blisters in the esophagus are rare, especially when there are no oral blisters. We report a case of newly diagnosed BP in a 48-year-old woman. She was admitted to our hospital with the sudden onset of hematemesis. This case highlights the importance of gastroenterologists who are cognizant of the potential association between skin illnesses and digestive disorders. It is important to exercise caution during endoscopic procedures in patients with pemphigoid disorders, especially in the absence of apparent symptoms. |
| format | Article |
| id | doaj-art-0ca8129194fb4e4dadbd3994644489ed |
| institution | Kabale University |
| issn | 2980-1818 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Caucasian Medical Journal |
| spelling | doaj-art-0ca8129194fb4e4dadbd3994644489ed2025-01-20T07:37:57ZengGalenos Publishing HouseCaucasian Medical Journal2980-18182024-11-0123343510.4274/cmj.galenos.2024.96268Esophageal Involvement and Bleeding in Bullous Pemphigoid DiseaseKerem Kenarlı0https://orcid.org/0000-0002-5952-2706Derya Arı1https://orcid.org/0000-0001-8024-781XMusa Caner Yılmaz2https://orcid.org/0000-0003-3260-3423Ankara Bilkent City Hospital, Clinic of Gastroenterology, Ankara, TurkeyAnkara Bilkent City Hospital, Clinic of Gastroenterology, Ankara, TurkeyAnkara Bilkent City Hospital, Clinic of Internal Medicine, Ankara, TurkeyBullous pemphigoid (BP) is the most common autoimmune bullous disorder and is characterized by autoantibodies against hemidesmosomal proteins in the skin and mucous membranes. BP typically presents as large, fluid-filled blisters on normal skin or red, enflamed areas of skin, mainly in the armpits, lower abdomen, inner thighs, and groin. Blisters on the lining of the oral and pharyngeal mucosa occur in up to 35% of cases, but blisters in the esophagus are rare, especially when there are no oral blisters. We report a case of newly diagnosed BP in a 48-year-old woman. She was admitted to our hospital with the sudden onset of hematemesis. This case highlights the importance of gastroenterologists who are cognizant of the potential association between skin illnesses and digestive disorders. It is important to exercise caution during endoscopic procedures in patients with pemphigoid disorders, especially in the absence of apparent symptoms.https://caucasianmedj.com/articles/esophageal-involvement-and-bleeding-in-bullous-pemphigoid-disease/doi/cmj.galenos.2024.96268bullous pemphigoidhematemesisendoscopy |
| spellingShingle | Kerem Kenarlı Derya Arı Musa Caner Yılmaz Esophageal Involvement and Bleeding in Bullous Pemphigoid Disease Caucasian Medical Journal bullous pemphigoid hematemesis endoscopy |
| title | Esophageal Involvement and Bleeding in Bullous Pemphigoid Disease |
| title_full | Esophageal Involvement and Bleeding in Bullous Pemphigoid Disease |
| title_fullStr | Esophageal Involvement and Bleeding in Bullous Pemphigoid Disease |
| title_full_unstemmed | Esophageal Involvement and Bleeding in Bullous Pemphigoid Disease |
| title_short | Esophageal Involvement and Bleeding in Bullous Pemphigoid Disease |
| title_sort | esophageal involvement and bleeding in bullous pemphigoid disease |
| topic | bullous pemphigoid hematemesis endoscopy |
| url | https://caucasianmedj.com/articles/esophageal-involvement-and-bleeding-in-bullous-pemphigoid-disease/doi/cmj.galenos.2024.96268 |
| work_keys_str_mv | AT keremkenarlı esophagealinvolvementandbleedinginbullouspemphigoiddisease AT deryaarı esophagealinvolvementandbleedinginbullouspemphigoiddisease AT musacaneryılmaz esophagealinvolvementandbleedinginbullouspemphigoiddisease |