Transmembrane Protein-184A Interacts with Syndecan-4 and Rab GTPases and Is Required to Maintain VE-Cadherin Levels

Transmembrane Protein-184A Interacts with Syndecan-4 and Rab GTPases and Is Required to Maintain VE-Cadherin Levels

VE-cadherin (VE-cad) membrane stability and localization regulates adhesion formation and actin cytoskeleton dynamics in angiogenesis and vascular remodeling and requires the heparan sulfate proteoglycan (HSPG), Syndecan-4 (Sdc4). This study characterizes the interactions of the heparin receptor, Tr...

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Bibliographic Details
Main Authors: Leanna M. Altenburg, Stephanie H. Wang, Grace O. Ciabattoni, Amelia Kennedy, Rachel L. O’Toole, Sara L. N. Farwell, M. Kathryn Iovine, Linda J. Lowe-Krentz
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
VE-cadherin
TMEM184A
syndecan-4
endothelial cells
angiogenesis
Online Access:https://www.mdpi.com/2073-4409/14/11/833
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