Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients
Prurigo pigmentosa is a unique cutaneous inflammatory disorder characterized by a sudden onset of pruritic and erythematous macules, urticarial papules, and plaques that may coalesce to form a reticulated pattern. Lesions typically heal within weeks leaving a reticulated and mottled postinflammatory...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/9406797 |
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| author | N. Almaani A. H. Al-Tarawneh H. Msallam |
| author_facet | N. Almaani A. H. Al-Tarawneh H. Msallam |
| author_sort | N. Almaani |
| collection | DOAJ |
| description | Prurigo pigmentosa is a unique cutaneous inflammatory disorder characterized by a sudden onset of pruritic and erythematous macules, urticarial papules, and plaques that may coalesce to form a reticulated pattern. Lesions typically heal within weeks leaving a reticulated and mottled postinflammatory hyperpigmentation. The majority of reported cases originate from Japan with much fewer cases described worldwide without predominant ethnicity. The histopathological features of prurigo pigmentosa can be nonspecific; however, distinct features exist for each stage of the disease. The aetiology of prurigo pigmentosa is not fully understood. However, ketoacidosis has been implicated in the pathogenesis and indeed prurigo pigmentosa has been associated with ketoacidotic states such as diabetes mellitus, fasting, dieting, and anorexia nervosa. In this report, we present 3 Jordanian patients with prurigo pigmentosa and describe their clinicopathological features. One patient developed prurigo pigmentosa while fasting during the month of Ramadan and another was undertaking a strict diet. No associations were identified in the third patient. In view of the largely nonspecific clinical and histological features, a high index of suspicion is required as many cases of prurigo pigmentosa are probably undiagnosed. |
| format | Article |
| id | doaj-art-0ca169c304ae4fe4beb1009a99cce8d7 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-0ca169c304ae4fe4beb1009a99cce8d72025-02-03T05:58:29ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712018-01-01201810.1155/2018/94067979406797Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern PatientsN. Almaani0A. H. Al-Tarawneh1H. Msallam2Department of Dermatology, Faculty of Medicine, The University of Jordan, Amman, JordanDepartment of Dermatology, Jordan University Hospital, Amman, JordanDepartment of Dermatology, Jordan University Hospital, Amman, JordanPrurigo pigmentosa is a unique cutaneous inflammatory disorder characterized by a sudden onset of pruritic and erythematous macules, urticarial papules, and plaques that may coalesce to form a reticulated pattern. Lesions typically heal within weeks leaving a reticulated and mottled postinflammatory hyperpigmentation. The majority of reported cases originate from Japan with much fewer cases described worldwide without predominant ethnicity. The histopathological features of prurigo pigmentosa can be nonspecific; however, distinct features exist for each stage of the disease. The aetiology of prurigo pigmentosa is not fully understood. However, ketoacidosis has been implicated in the pathogenesis and indeed prurigo pigmentosa has been associated with ketoacidotic states such as diabetes mellitus, fasting, dieting, and anorexia nervosa. In this report, we present 3 Jordanian patients with prurigo pigmentosa and describe their clinicopathological features. One patient developed prurigo pigmentosa while fasting during the month of Ramadan and another was undertaking a strict diet. No associations were identified in the third patient. In view of the largely nonspecific clinical and histological features, a high index of suspicion is required as many cases of prurigo pigmentosa are probably undiagnosed.http://dx.doi.org/10.1155/2018/9406797 |
| spellingShingle | N. Almaani A. H. Al-Tarawneh H. Msallam Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients Case Reports in Dermatological Medicine |
| title | Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients |
| title_full | Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients |
| title_fullStr | Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients |
| title_full_unstemmed | Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients |
| title_short | Prurigo Pigmentosa: A Clinicopathological Report of Three Middle Eastern Patients |
| title_sort | prurigo pigmentosa a clinicopathological report of three middle eastern patients |
| url | http://dx.doi.org/10.1155/2018/9406797 |
| work_keys_str_mv | AT nalmaani prurigopigmentosaaclinicopathologicalreportofthreemiddleeasternpatients AT ahaltarawneh prurigopigmentosaaclinicopathologicalreportofthreemiddleeasternpatients AT hmsallam prurigopigmentosaaclinicopathologicalreportofthreemiddleeasternpatients |