The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon province
Abstract Background: Rhinitis is defined as inflammation of the mucous membranes of the nose usually that is accompanied by swelling of the mucosa and a nasal discharge. It is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens, smoking and alcohol use, gender, age, overweight,...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Medical Journal of Babylon |
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| Online Access: | https://doi.org/10.4103/MJBL.MJBL_161_23 |
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| author | Bushra Jihad Sabbar Zenaa Abbass Ali Tariq Hussein Mgheer |
| author_facet | Bushra Jihad Sabbar Zenaa Abbass Ali Tariq Hussein Mgheer |
| author_sort | Bushra Jihad Sabbar |
| collection | DOAJ |
| description | Abstract Background: Rhinitis is defined as inflammation of the mucous membranes of the nose usually that is accompanied by swelling of the mucosa and a nasal discharge. It is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens, smoking and alcohol use, gender, age, overweight, adoption of pets, race, educational achievement, and family history can represent a risk factor for allergic rhinitis (AR). Objectives: To find the effect of electrolytes tumor necrosis factor (TNF)-α and IgE on AR and study the influence of smoking, gender, and obesity (as a risk factor on AR) on the levels of TNF-α and IgE. Materials and Methods: Eighty subjects for this study were enrolled; 40 of those who have AR age ranged between 18 and 50 years. A control group of 40 subjects who appear to be in good health was selected. This study is a case–control study. TNF-alpha concentration and immunoglobulin-E were measured in serum by an enzyme-linked immunosorbent assay (ELISA) technique also The electrolytes concentrations were measured in the serum using an Abbott device with Integrated Chip Technology (ICT) human kit. The electrolytes were also measured in the serum using the Abbott device. Full history was taken from all patients, which include age, residence, smoking, body mass index, and family history of AR. Results: The results reveal a significant difference (P < 0.05) in levels of TNF-α, Ig-E between patients and controls, There was no significant difference between smoker and non- smoker, normal weight and overweight groups in patients and controls groups. |
| format | Article |
| id | doaj-art-0ca14b21899e4a9c9bd85f3158c5fe86 |
| institution | Kabale University |
| issn | 1812-156X 2312-6760 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Babylon |
| spelling | doaj-art-0ca14b21899e4a9c9bd85f3158c5fe862025-01-25T10:14:50ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602024-01-01211353810.4103/MJBL.MJBL_161_23The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon provinceBushra Jihad SabbarZenaa Abbass AliTariq Hussein MgheerAbstract Background: Rhinitis is defined as inflammation of the mucous membranes of the nose usually that is accompanied by swelling of the mucosa and a nasal discharge. It is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens, smoking and alcohol use, gender, age, overweight, adoption of pets, race, educational achievement, and family history can represent a risk factor for allergic rhinitis (AR). Objectives: To find the effect of electrolytes tumor necrosis factor (TNF)-α and IgE on AR and study the influence of smoking, gender, and obesity (as a risk factor on AR) on the levels of TNF-α and IgE. Materials and Methods: Eighty subjects for this study were enrolled; 40 of those who have AR age ranged between 18 and 50 years. A control group of 40 subjects who appear to be in good health was selected. This study is a case–control study. TNF-alpha concentration and immunoglobulin-E were measured in serum by an enzyme-linked immunosorbent assay (ELISA) technique also The electrolytes concentrations were measured in the serum using an Abbott device with Integrated Chip Technology (ICT) human kit. The electrolytes were also measured in the serum using the Abbott device. Full history was taken from all patients, which include age, residence, smoking, body mass index, and family history of AR. Results: The results reveal a significant difference (P < 0.05) in levels of TNF-α, Ig-E between patients and controls, There was no significant difference between smoker and non- smoker, normal weight and overweight groups in patients and controls groups.https://doi.org/10.4103/MJBL.MJBL_161_23allergic rhinitiselectrolytesenzyme-linked immunosorbent assay (elisa)igetumor necrosis factor-alpha |
| spellingShingle | Bushra Jihad Sabbar Zenaa Abbass Ali Tariq Hussein Mgheer The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon province Medical Journal of Babylon allergic rhinitis electrolytes enzyme-linked immunosorbent assay (elisa) ige tumor necrosis factor-alpha |
| title | The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon province |
| title_full | The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon province |
| title_fullStr | The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon province |
| title_full_unstemmed | The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon province |
| title_short | The Relationship of immunoglobulin-e and tumor necrosis factor in patients with allergic rhinitis in Babylon province |
| title_sort | relationship of immunoglobulin e and tumor necrosis factor in patients with allergic rhinitis in babylon province |
| topic | allergic rhinitis electrolytes enzyme-linked immunosorbent assay (elisa) ige tumor necrosis factor-alpha |
| url | https://doi.org/10.4103/MJBL.MJBL_161_23 |
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