Development and application of an LC–MS/MS method for quantification of fosmidomycin in human and rat plasma

Development and application of an LC–MS/MS method for quantification of fosmidomycin in human and rat plasma

Abstract Background Malaria still poses a significant burden on global health, with millions of cases reported annually and rising resistance to current treatments, emphasizing the need for new therapeutic strategies. Fosmidomycin, initially recognized for its antibacterial properties, has emerged a...

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Main Authors: Christoph Pfaffendorf, Keanu D. Sackmann, Johannes Mischlinger, Jean Claude Dejon-Agobé, Oumou Maïga-Ascofaré, Ebenezer Ahenkan, Ayôla Akim Adegnika, Michael Ramharter, Philipp Uhl, Gert Fricker, Sebastian G. Wicha
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Malaria Journal
Subjects:
Fosmidomycin
LC–MS/MS
Pharmacokinetics
Bioanalysis
Malaria
Online Access:https://doi.org/10.1186/s12936-025-05489-1
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