ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same Case
Introduction. Liver involvement due to hyperthyroidism and also ANCA positive vasculitis related renal failure cases were reported separately several times before. However, to our knowledge, these two complications together in the same case had never been observed before. Case Presentation. The cas...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2014/762528 |
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| author | Mehmet Tuncay Emine Kivrakoglu Itir Yegenaga Erkan Dervisoglu |
| author_facet | Mehmet Tuncay Emine Kivrakoglu Itir Yegenaga Erkan Dervisoglu |
| author_sort | Mehmet Tuncay |
| collection | DOAJ |
| description | Introduction. Liver involvement due to hyperthyroidism and also ANCA positive vasculitis related renal failure cases were reported separately several times before. However, to our knowledge, these two complications together in the same case had never been observed before. Case Presentation. The case of an ANCA positive 71-year-old Caucasian male with renal failure and lung involvement, subclinical hyperthyroidism, and intrahepatic cholestatic jaundice was presented in this paper. After exclusion of all of the other possibilities, cholestatic hepatitis was explained by subclinical hyperthyroidism; renal failure and lung involvement were interpreted as ANCA related vasculitis which might be a side effect of propylthiouracil use. Conclusion. The coexistence of these rare conditions in the same patient deserves emphasis and it is worth reporting. This case demonstrates that following the clinical course of the patient is essential after prescribing any medications to see whether any complication occurs or not. If the complications of this case were noticed earlier, it would be possible to treat and to prevent the permanent damages. |
| format | Article |
| id | doaj-art-0c871dccdc3e42c7af293f4e65380b56 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-0c871dccdc3e42c7af293f4e65380b562025-02-03T01:22:37ZengWileyCase Reports in Nephrology2090-66412090-665X2014-01-01201410.1155/2014/762528762528ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same CaseMehmet Tuncay0Emine Kivrakoglu1Itir Yegenaga2Erkan Dervisoglu3Department of Internal Medicine, Medical School Kocaeli University, 41380 Kocaeli, TurkeyDepartment of Internal Medicine, Medical School Kocaeli University, 41380 Kocaeli, TurkeyDepartment of Internal Medicine, Medical School Kocaeli University, 41380 Kocaeli, TurkeyDepartment of Internal Medicine, Medical School Kocaeli University, 41380 Kocaeli, TurkeyIntroduction. Liver involvement due to hyperthyroidism and also ANCA positive vasculitis related renal failure cases were reported separately several times before. However, to our knowledge, these two complications together in the same case had never been observed before. Case Presentation. The case of an ANCA positive 71-year-old Caucasian male with renal failure and lung involvement, subclinical hyperthyroidism, and intrahepatic cholestatic jaundice was presented in this paper. After exclusion of all of the other possibilities, cholestatic hepatitis was explained by subclinical hyperthyroidism; renal failure and lung involvement were interpreted as ANCA related vasculitis which might be a side effect of propylthiouracil use. Conclusion. The coexistence of these rare conditions in the same patient deserves emphasis and it is worth reporting. This case demonstrates that following the clinical course of the patient is essential after prescribing any medications to see whether any complication occurs or not. If the complications of this case were noticed earlier, it would be possible to treat and to prevent the permanent damages.http://dx.doi.org/10.1155/2014/762528 |
| spellingShingle | Mehmet Tuncay Emine Kivrakoglu Itir Yegenaga Erkan Dervisoglu ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same Case Case Reports in Nephrology |
| title | ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same Case |
| title_full | ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same Case |
| title_fullStr | ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same Case |
| title_full_unstemmed | ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same Case |
| title_short | ANCA Associated Vasculitis and Renal Failure Related to Propylthiouracil and Hyperthyroidism Induced Cholestasis in the Same Case |
| title_sort | anca associated vasculitis and renal failure related to propylthiouracil and hyperthyroidism induced cholestasis in the same case |
| url | http://dx.doi.org/10.1155/2014/762528 |
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