A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case report
Background Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible neurotoxicity. The symptoms include headache, altered consciousness, seizures, visual disturbances, and focal neurological deficits. The severe variant, known as malignant PRES, is rare and involves diffuse...
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The Korean Neurocritical Care Society
2024-12-01
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| Series: | Journal of Neurocritical Care |
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| Online Access: | http://e-jnc.org/upload/pdf/jnc-240019.pdf |
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| author | Ojas Unavane Tushar Premraj Raut Lakhan Parajiya Alisha Rajan Sadarangani |
| author_facet | Ojas Unavane Tushar Premraj Raut Lakhan Parajiya Alisha Rajan Sadarangani |
| author_sort | Ojas Unavane |
| collection | DOAJ |
| description | Background Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible neurotoxicity. The symptoms include headache, altered consciousness, seizures, visual disturbances, and focal neurological deficits. The severe variant, known as malignant PRES, is rare and involves diffuse cerebral edema, leading to irreversible damage. Chronic kidney disease (CKD) with impaired blood pressure regulation is a known risk factor for malignant PRES. Case report We report the case of a patient with CKD who presented with hypertensive crisis and later developed malignant PRES in the background of status epilepticus refractory to antiepileptic treatment. Conclusions This case highlights the importance of considering malignant PRES in hypertensive crises and emphasizes the need for further research to elucidate its pathophysiology and develop effective treatment strategies. |
| format | Article |
| id | doaj-art-0c7ffa55f76b45a38aec831a96ae25a1 |
| institution | DOAJ |
| issn | 2005-0348 2508-1349 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | The Korean Neurocritical Care Society |
| record_format | Article |
| series | Journal of Neurocritical Care |
| spelling | doaj-art-0c7ffa55f76b45a38aec831a96ae25a12025-08-20T02:58:19ZengThe Korean Neurocritical Care SocietyJournal of Neurocritical Care2005-03482508-13492024-12-01172626610.18700/jnc.240019415A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case reportOjas Unavane0Tushar Premraj Raut1Lakhan Parajiya2Alisha Rajan Sadarangani3 Department of General Medicine, Kokilaben Dhirubhai Ambani Hospital and Medical Research Center, Mumbai, India Department of Neurology Medicine, Kokilaben Dhirubhai Ambani Hospital and Medical Research Center, Mumbai, India Department of Neurology Medicine, Kokilaben Dhirubhai Ambani Hospital and Medical Research Center, Mumbai, India Department of Neurology Medicine, Kokilaben Dhirubhai Ambani Hospital and Medical Research Center, Mumbai, IndiaBackground Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible neurotoxicity. The symptoms include headache, altered consciousness, seizures, visual disturbances, and focal neurological deficits. The severe variant, known as malignant PRES, is rare and involves diffuse cerebral edema, leading to irreversible damage. Chronic kidney disease (CKD) with impaired blood pressure regulation is a known risk factor for malignant PRES. Case report We report the case of a patient with CKD who presented with hypertensive crisis and later developed malignant PRES in the background of status epilepticus refractory to antiepileptic treatment. Conclusions This case highlights the importance of considering malignant PRES in hypertensive crises and emphasizes the need for further research to elucidate its pathophysiology and develop effective treatment strategies.http://e-jnc.org/upload/pdf/jnc-240019.pdfcase reportposterior reversible encephalopathy syndromehypertensive crisisstatus epilepticus |
| spellingShingle | Ojas Unavane Tushar Premraj Raut Lakhan Parajiya Alisha Rajan Sadarangani A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case report Journal of Neurocritical Care case report posterior reversible encephalopathy syndrome hypertensive crisis status epilepticus |
| title | A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case report |
| title_full | A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case report |
| title_fullStr | A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case report |
| title_full_unstemmed | A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case report |
| title_short | A fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus: a case report |
| title_sort | fatal case of malignant posterior reversible encephalopathy syndrome in the setting of status epilepticus a case report |
| topic | case report posterior reversible encephalopathy syndrome hypertensive crisis status epilepticus |
| url | http://e-jnc.org/upload/pdf/jnc-240019.pdf |
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