Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya
Objective. To determine the factors associated with poor blood pressure control among renal transplant recipients in a resource-limited setting. Methods. A cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital. Sociodemographic details, blood pressure...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2015/746563 |
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| author | Mary N. Kubo Joshua K. Kayima Anthony J. Were Seth O. McLigeyo Elijah N. Ogola |
| author_facet | Mary N. Kubo Joshua K. Kayima Anthony J. Were Seth O. McLigeyo Elijah N. Ogola |
| author_sort | Mary N. Kubo |
| collection | DOAJ |
| description | Objective. To determine the factors associated with poor blood pressure control among renal transplant recipients in a resource-limited setting. Methods. A cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital. Sociodemographic details, blood pressure, urine albumin : creatinine ratio, and adherence using the MMAS-8 questionnaire were noted. Independent factors associated with uncontrolled hypertension were determined using logistic regression analysis. Results. 85 subjects were evaluated. Mean age was 42.4 (SD ± 12.2) years, with a male : female ratio of 1.9 : 1. Fifty-five patients (64.7%) had uncontrolled hypertension (BP ≥ 130/80 mmHg). On univariate analysis, male sex (OR 3.7, 95% CI 1.4–9.5, p=0.006), higher levels of proteinuria (p=0.042), and nonadherence to antihypertensives (OR 18, 95% CI 5.2–65.7, p<0.001) were associated with uncontrolled hypertension. On logistic regression analysis, male sex (adjusted OR 4.6, 95% CI 1.1–19.0, p=0.034) and nonadherence (adjusted OR 33.8, 95% CI 8.6–73.0, p<0.001) were independently associated with uncontrolled hypertension. Conclusion. Factors associated with poor blood pressure control in this cohort were male sex and nonadherence to antihypertensives. Emphasis on adherence to antihypertensive therapy must be pursued within this population. |
| format | Article |
| id | doaj-art-0c78c8b873af48c2a82bef360ac05973 |
| institution | Kabale University |
| issn | 2090-0007 2090-0015 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Transplantation |
| spelling | doaj-art-0c78c8b873af48c2a82bef360ac059732025-02-03T01:23:28ZengWileyJournal of Transplantation2090-00072090-00152015-01-01201510.1155/2015/746563746563Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, KenyaMary N. Kubo0Joshua K. Kayima1Anthony J. Were2Seth O. McLigeyo3Elijah N. Ogola4Department of Clinical Medicine and Therapeutics, University of Nairobi (UoN), P.O. Box 60337-00200, Nairobi, KenyaDepartment of Clinical Medicine and Therapeutics, University of Nairobi (UoN), P.O. Box 60337-00200, Nairobi, KenyaDepartment of Clinical Medicine and Therapeutics, University of Nairobi (UoN), P.O. Box 60337-00200, Nairobi, KenyaDepartment of Clinical Medicine and Therapeutics, University of Nairobi (UoN), P.O. Box 60337-00200, Nairobi, KenyaDepartment of Clinical Medicine and Therapeutics, University of Nairobi (UoN), P.O. Box 60337-00200, Nairobi, KenyaObjective. To determine the factors associated with poor blood pressure control among renal transplant recipients in a resource-limited setting. Methods. A cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital. Sociodemographic details, blood pressure, urine albumin : creatinine ratio, and adherence using the MMAS-8 questionnaire were noted. Independent factors associated with uncontrolled hypertension were determined using logistic regression analysis. Results. 85 subjects were evaluated. Mean age was 42.4 (SD ± 12.2) years, with a male : female ratio of 1.9 : 1. Fifty-five patients (64.7%) had uncontrolled hypertension (BP ≥ 130/80 mmHg). On univariate analysis, male sex (OR 3.7, 95% CI 1.4–9.5, p=0.006), higher levels of proteinuria (p=0.042), and nonadherence to antihypertensives (OR 18, 95% CI 5.2–65.7, p<0.001) were associated with uncontrolled hypertension. On logistic regression analysis, male sex (adjusted OR 4.6, 95% CI 1.1–19.0, p=0.034) and nonadherence (adjusted OR 33.8, 95% CI 8.6–73.0, p<0.001) were independently associated with uncontrolled hypertension. Conclusion. Factors associated with poor blood pressure control in this cohort were male sex and nonadherence to antihypertensives. Emphasis on adherence to antihypertensive therapy must be pursued within this population.http://dx.doi.org/10.1155/2015/746563 |
| spellingShingle | Mary N. Kubo Joshua K. Kayima Anthony J. Were Seth O. McLigeyo Elijah N. Ogola Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya Journal of Transplantation |
| title | Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya |
| title_full | Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya |
| title_fullStr | Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya |
| title_full_unstemmed | Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya |
| title_short | Factors Associated with Uncontrolled Hypertension among Renal Transplant Recipients Attending Nephrology Clinics in Nairobi, Kenya |
| title_sort | factors associated with uncontrolled hypertension among renal transplant recipients attending nephrology clinics in nairobi kenya |
| url | http://dx.doi.org/10.1155/2015/746563 |
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