M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer

M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer

Background The immunological microenvironment of primary high-grade serous carcinomas (HGSCs) has a major impact on disease outcome. Conversely, little is known on the microenvironment of metastatic HGSCs and its potential influence on patient survival. Here, we explore the clinical relevance of the...

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Main Authors: Vladimir Benes, Ladislav Pecen, Jelena Pistolic, Lorenzo Galluzzi, Iva Truxova, Radek Špíšek, Lenka Kasikova, Michal Hensler, Petr Skapa, Jan Laco, Ivan Praznovec, Tomas Brtnicky, Lukas Rob, Catherine Sautes-Fridman, Ales Ryska, Jitka Fucikova, Wolf Herve Fridman, Vít Drochýtek, Sarka Vosahlikova, Karel Fiser, Jana Rakova, Tereza Lanickova, Irena Moserova, Martina Rehackova, Ludek Sojka
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000979.full
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