Neuregulin1 ameliorates metabolic dysfunction-associated fatty liver disease via the ERK/SIRT1 signaling pathways

Neuregulin1 ameliorates metabolic dysfunction-associated fatty liver disease via the ERK/SIRT1 signaling pathways

Abstract Background Neuregulin (NRG) family is involved in energy metabolism, among which NRG1 is a neuregulin proved to play a protective role in MAFLD cells. But the presice echanism has not been fully illustrated. This study aimed to investigate the role of NRG1 via the ERK/SIRT1 signaling in the...

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Bibliographic Details
Main Authors: Chengan Xu, Shouhao Wang, Di Meng, Mingshan Wang, Rong Yan, Yining Dai
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Gastroenterology
Subjects:
Metabolic dysfunction-associated fatty liver disease
Neuregulin 1
ERK
SIRT1
Autophagy
Online Access:https://doi.org/10.1186/s12876-025-03632-5
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