Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literature
Fibroblastic reticular cell tumours (FRCT) originate from the fibroblastic reticular cells (FBRC) which are histiocytic cells, belonging to the dendritic cell family. These tumours are extremely rare, with only a few cases reported in literature. Histomorphologically, they resemble follicular dendri...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_908_21 |
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| author | Pragnya P. Mishra K Madan Siddhartha Biswas Anuradha Calicut Kini Rao |
| author_facet | Pragnya P. Mishra K Madan Siddhartha Biswas Anuradha Calicut Kini Rao |
| author_sort | Pragnya P. Mishra |
| collection | DOAJ |
| description | Fibroblastic reticular cell tumours (FRCT) originate from the fibroblastic reticular cells (FBRC) which are histiocytic cells, belonging to the dendritic cell family. These tumours are extremely rare, with only a few cases reported in literature. Histomorphologically, they resemble follicular dendritic cell sarcoma (FDCS); however, they differ immunophenotypically. Extranodal presentations are rare. We report a case of malignant FBRC tumour of the left eyelid, in a 23-year-old woman, who had presented with a recurrent swelling over left lower eyelid. Microscopy revealed an ill circumbscribed tumour composed of oval to spindle cells in storiform pattern, sprinkled with lymphocytes. Immunohistochemistry was performed and diagnosis of FRCT was offered. To the best of our knowledge, this is the first report of malignant FBRC tumour arising in the eyelid region. Here we present this extremely rare case with review of the available literature. |
| format | Article |
| id | doaj-art-0c606878548d4729bd7ca0c0860fbe23 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-0c606878548d4729bd7ca0c0860fbe232025-01-22T15:13:19ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302023-01-0167116616810.4103/ijpm.ijpm_908_21Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literaturePragnya P. MishraK MadanSiddhartha BiswasAnuradha Calicut Kini RaoFibroblastic reticular cell tumours (FRCT) originate from the fibroblastic reticular cells (FBRC) which are histiocytic cells, belonging to the dendritic cell family. These tumours are extremely rare, with only a few cases reported in literature. Histomorphologically, they resemble follicular dendritic cell sarcoma (FDCS); however, they differ immunophenotypically. Extranodal presentations are rare. We report a case of malignant FBRC tumour of the left eyelid, in a 23-year-old woman, who had presented with a recurrent swelling over left lower eyelid. Microscopy revealed an ill circumbscribed tumour composed of oval to spindle cells in storiform pattern, sprinkled with lymphocytes. Immunohistochemistry was performed and diagnosis of FRCT was offered. To the best of our knowledge, this is the first report of malignant FBRC tumour arising in the eyelid region. Here we present this extremely rare case with review of the available literature.https://journals.lww.com/10.4103/ijpm.ijpm_908_21dendritic cellseyelid tumourfibroblastic reticular cell tumours |
| spellingShingle | Pragnya P. Mishra K Madan Siddhartha Biswas Anuradha Calicut Kini Rao Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literature Indian Journal of Pathology and Microbiology dendritic cells eyelid tumour fibroblastic reticular cell tumours |
| title | Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literature |
| title_full | Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literature |
| title_fullStr | Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literature |
| title_full_unstemmed | Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literature |
| title_short | Fibroblastic reticular cell tumor of eyelid: Rare case report and review of literature |
| title_sort | fibroblastic reticular cell tumor of eyelid rare case report and review of literature |
| topic | dendritic cells eyelid tumour fibroblastic reticular cell tumours |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_908_21 |
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