Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction
Persistent organic pollutants (POPs), such as polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs), and polybrominated ethers (PBDEs), chloronaftalens (PCNs), and bisphenol A (BPA), are stable, lipophilic pollutants that affect fertility and cause ser...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/828532 |
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| author | Ewa L. Gregoraszczuk Anna Ptak |
| author_facet | Ewa L. Gregoraszczuk Anna Ptak |
| author_sort | Ewa L. Gregoraszczuk |
| collection | DOAJ |
| description | Persistent organic pollutants (POPs), such as polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs), and polybrominated ethers (PBDEs), chloronaftalens (PCNs), and bisphenol A (BPA), are stable, lipophilic pollutants that affect fertility and cause serious reproductive problems, including ovotoxic action, lack of ovulation, premature ovarian failure (POF), or polycystic ovarian syndrome (PCOS). Most of the representatives of POPs influence the activation of transcription factors, not only activation of aromatic hydrocarbon receptor (AhR), but also the steroid hormone receptors. This minireview will focus on a variety of PAH activities in oocyte, ovary, placenta, and mammary gland. The complexity and diversity of factors belonging to POPs and disorders of the reproductive function of women indicate that the impact of environmental pollution as an important determinant factor in fertility should not be minimize. |
| format | Article |
| id | doaj-art-0c373a77fce649579be087fee8992658 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-0c373a77fce649579be087fee89926582025-02-03T01:30:12ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/828532828532Endocrine-Disrupting Chemicals: Some Actions of POPs on Female ReproductionEwa L. Gregoraszczuk0Anna Ptak1Department of Physiology and Toxicology of Reproduction, Institute of Zoology, Jagiellonian University, Gronostajowa 9, 30-387 Krakow, PolandDepartment of Physiology and Toxicology of Reproduction, Institute of Zoology, Jagiellonian University, Gronostajowa 9, 30-387 Krakow, PolandPersistent organic pollutants (POPs), such as polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs), and polybrominated ethers (PBDEs), chloronaftalens (PCNs), and bisphenol A (BPA), are stable, lipophilic pollutants that affect fertility and cause serious reproductive problems, including ovotoxic action, lack of ovulation, premature ovarian failure (POF), or polycystic ovarian syndrome (PCOS). Most of the representatives of POPs influence the activation of transcription factors, not only activation of aromatic hydrocarbon receptor (AhR), but also the steroid hormone receptors. This minireview will focus on a variety of PAH activities in oocyte, ovary, placenta, and mammary gland. The complexity and diversity of factors belonging to POPs and disorders of the reproductive function of women indicate that the impact of environmental pollution as an important determinant factor in fertility should not be minimize.http://dx.doi.org/10.1155/2013/828532 |
| spellingShingle | Ewa L. Gregoraszczuk Anna Ptak Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction International Journal of Endocrinology |
| title | Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction |
| title_full | Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction |
| title_fullStr | Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction |
| title_full_unstemmed | Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction |
| title_short | Endocrine-Disrupting Chemicals: Some Actions of POPs on Female Reproduction |
| title_sort | endocrine disrupting chemicals some actions of pops on female reproduction |
| url | http://dx.doi.org/10.1155/2013/828532 |
| work_keys_str_mv | AT ewalgregoraszczuk endocrinedisruptingchemicalssomeactionsofpopsonfemalereproduction AT annaptak endocrinedisruptingchemicalssomeactionsofpopsonfemalereproduction |