Anti-diabetic effect of aloin via JNK-IRS1/PI3K pathways and regulation of gut microbiota

Anti-diabetic effect of aloin via JNK-IRS1/PI3K pathways and regulation of gut microbiota

This research aimed to investigate the antidiabetic activity, underlying mechanisms, and gut microbiota regulation of aloin. The insulin-resistant HepG2 (IR-HepG2) cell model and the type 2 diabetic (T2D) mouse model were successfully established using dexamethasone and a high-fat high-sucrose diet...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruting Zhong, Lanbin Chen, Yuanyuan Liu, Shouxia Xie, Sumei Li, Bin Liu, Chao Zhao
Format: Article
Language:English
Published: Tsinghua University Press 2022-01-01
Series:Food Science and Human Wellness
Subjects:
Aloin
Antidiabetic
Gut microbiota
Insulin signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453021000859
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items