Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter
Fosetyl-aluminum is a synthetic fungicide administered to plants especially to prevent diseases caused by the members of the Peronosporales and several Phytophthora species. Herein, we present a selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze residues of fosetyl...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2018/8792085 |
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| author | Francesca Buiarelli Patrizia Di Filippo Carmela Riccardi Donatella Pomata Riccardo Marsiglia Carla Console Daniele Puri |
| author_facet | Francesca Buiarelli Patrizia Di Filippo Carmela Riccardi Donatella Pomata Riccardo Marsiglia Carla Console Daniele Puri |
| author_sort | Francesca Buiarelli |
| collection | DOAJ |
| description | Fosetyl-aluminum is a synthetic fungicide administered to plants especially to prevent diseases caused by the members of the Peronosporales and several Phytophthora species. Herein, we present a selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze residues of fosetyl-A1 in air particulate matter. This study was performed in perspective of an exposure assessment of this substance of health concern in environments where high levels of fosetly-Al, relatively to airborne particulate matter, can be found after spraying it. The cleanup procedure of the analyte, from sampled filters of atmospheric particulate matter, was optimized using a Strata X solid-phase extraction cartridge, after accelerated extraction by using water. The chromatographic separation was achieved using a polymeric column based on hydrophilic interaction in step elution with water/acetonitrile, whereas the mass spectrometric detection was performed in negative electrospray ionization. The proposed method resulted to be a simple, fast, and suitable method for confirmation purposes. |
| format | Article |
| id | doaj-art-0c069167ca8949af92c6fdf3551bcb81 |
| institution | Kabale University |
| issn | 2090-8865 2090-8873 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-0c069167ca8949af92c6fdf3551bcb812025-02-03T06:08:12ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732018-01-01201810.1155/2018/87920858792085Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate MatterFrancesca Buiarelli0Patrizia Di Filippo1Carmela Riccardi2Donatella Pomata3Riccardo Marsiglia4Carla Console5Daniele Puri6Department of Chemistry, University “Sapienza”, Piazzale Aldo Moro, 5-0185 Rome, ItalyDepartment of Chemistry, University “Sapienza”, Piazzale Aldo Moro, 5-0185 Rome, ItalyDepartment of Chemistry, University “Sapienza”, Piazzale Aldo Moro, 5-0185 Rome, ItalyDepartment of Chemistry, University “Sapienza”, Piazzale Aldo Moro, 5-0185 Rome, ItalyDepartment of Chemistry, University “Sapienza”, Piazzale Aldo Moro, 5-0185 Rome, ItalyDIT, INAIL, Via di Fontana Candida, 1-00040 Monteporzio Catone, Rome, ItalyDIT, INAIL, Via di Fontana Candida, 1-00040 Monteporzio Catone, Rome, ItalyFosetyl-aluminum is a synthetic fungicide administered to plants especially to prevent diseases caused by the members of the Peronosporales and several Phytophthora species. Herein, we present a selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze residues of fosetyl-A1 in air particulate matter. This study was performed in perspective of an exposure assessment of this substance of health concern in environments where high levels of fosetly-Al, relatively to airborne particulate matter, can be found after spraying it. The cleanup procedure of the analyte, from sampled filters of atmospheric particulate matter, was optimized using a Strata X solid-phase extraction cartridge, after accelerated extraction by using water. The chromatographic separation was achieved using a polymeric column based on hydrophilic interaction in step elution with water/acetonitrile, whereas the mass spectrometric detection was performed in negative electrospray ionization. The proposed method resulted to be a simple, fast, and suitable method for confirmation purposes.http://dx.doi.org/10.1155/2018/8792085 |
| spellingShingle | Francesca Buiarelli Patrizia Di Filippo Carmela Riccardi Donatella Pomata Riccardo Marsiglia Carla Console Daniele Puri Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter Journal of Analytical Methods in Chemistry |
| title | Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter |
| title_full | Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter |
| title_fullStr | Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter |
| title_full_unstemmed | Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter |
| title_short | Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry Analysis of Fosetyl-Aluminum in Airborne Particulate Matter |
| title_sort | hydrophilic interaction liquid chromatography tandem mass spectrometry analysis of fosetyl aluminum in airborne particulate matter |
| url | http://dx.doi.org/10.1155/2018/8792085 |
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