Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare Lesion
There has been an increasing use of hormonal therapy among male-to-female (MtF) transgender individuals. This long-term hormone replacement therapy (HRT) renders MtF individuals a unique patient subgroup in terms of breast cancer risk. This case describes a MtF transgender who presented with a breas...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/5172072 |
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| _version_ | 1832556590671069184 |
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| author | Krystina Tongson Victoria Konovalova Naveen Dhawan Steffi Sharma Jaya Bahl Mohammad Masri |
| author_facet | Krystina Tongson Victoria Konovalova Naveen Dhawan Steffi Sharma Jaya Bahl Mohammad Masri |
| author_sort | Krystina Tongson |
| collection | DOAJ |
| description | There has been an increasing use of hormonal therapy among male-to-female (MtF) transgender individuals. This long-term hormone replacement therapy (HRT) renders MtF individuals a unique patient subgroup in terms of breast cancer risk. This case describes a MtF transgender who presented with a breast lesion concerning for malignancy following hormonal replacement therapy. The patient additionally had a strong family history of breast cancer. Final pathology revealed lobular hyperplasia in the setting of gynecomastia and pseudoangiomatous stromal hyperplasia (PASH). Both pathology findings are rare in biological females, let alone in the setting of hormone replacement therapy in a MtF individual. While the number of reported cases of suspicious breast lesions in this population remains scarce, it presents both a diagnostic and therapeutic challenge due to the nature of the treatment course and the lack of research in this recently growing subgroup of patients. |
| format | Article |
| id | doaj-art-0bfc1728662a4dbfbb27ef4d5c71876a |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-0bfc1728662a4dbfbb27ef4d5c71876a2025-02-03T05:44:48ZengWileyCase Reports in Oncological Medicine2090-67062090-67142017-01-01201710.1155/2017/51720725172072Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare LesionKrystina Tongson0Victoria Konovalova1Naveen Dhawan2Steffi Sharma3Jaya Bahl4Mohammad Masri5Department of General Surgery, Larkin Community Hospital, South Miami, FL, USADepartment of General Surgery, Larkin Community Hospital, South Miami, FL, USADivision of Health Sciences, Nova Southeastern University, Davie, FL, USAKasturba Medical College, Manipal, IndiaFlorida International University (FIU), Miami, FL, USADepartment of General Surgery, Larkin Community Hospital, South Miami, FL, USAThere has been an increasing use of hormonal therapy among male-to-female (MtF) transgender individuals. This long-term hormone replacement therapy (HRT) renders MtF individuals a unique patient subgroup in terms of breast cancer risk. This case describes a MtF transgender who presented with a breast lesion concerning for malignancy following hormonal replacement therapy. The patient additionally had a strong family history of breast cancer. Final pathology revealed lobular hyperplasia in the setting of gynecomastia and pseudoangiomatous stromal hyperplasia (PASH). Both pathology findings are rare in biological females, let alone in the setting of hormone replacement therapy in a MtF individual. While the number of reported cases of suspicious breast lesions in this population remains scarce, it presents both a diagnostic and therapeutic challenge due to the nature of the treatment course and the lack of research in this recently growing subgroup of patients.http://dx.doi.org/10.1155/2017/5172072 |
| spellingShingle | Krystina Tongson Victoria Konovalova Naveen Dhawan Steffi Sharma Jaya Bahl Mohammad Masri Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare Lesion Case Reports in Oncological Medicine |
| title | Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare Lesion |
| title_full | Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare Lesion |
| title_fullStr | Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare Lesion |
| title_full_unstemmed | Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare Lesion |
| title_short | Breast Cancer Suspicion in a Transgender Male-to-Female Patient on Hormone Replacement Therapy Presenting with Right Breast Mass: Breast Cancer Risk Assessment and Presentation of a Rare Lesion |
| title_sort | breast cancer suspicion in a transgender male to female patient on hormone replacement therapy presenting with right breast mass breast cancer risk assessment and presentation of a rare lesion |
| url | http://dx.doi.org/10.1155/2017/5172072 |
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