Rectify the impact of shorter red blood cell lifespan upon HbA1c detection values in T2DM patients: modeling and internal-external verification

Rectify the impact of shorter red blood cell lifespan upon HbA1c detection values in T2DM patients: modeling and internal-external verification

AimsTo determine the effect of red blood cell (RBC) lifespan variability on glycosylated hemoglobin (HbA1c) measurements in type 2 diabetes mellitus (T2DM) individuals and develop a mathematical model for adjusting HbA1c values.MethodsWe tracked glucose levels in 516 T2DM patients from Chu Hsien-I M...

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Bibliographic Details
Main Authors:	Li Zhang, Ximan Gao, Xuying Meng, Guangyang Ma, Jing Li, Weilin Wang, Sisi Chen, Yongjian Ma, Pei Yu, Saijun Zhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Endocrinology
Subjects:	glycosylated hemoglobin (HbA1c) hemoglobin glycation index (HGI) red blood cell lifespan type 2 diabetes mellitus correction model
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1500660/full
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